Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/- |
Location | 6850..7481 | Replicon | chromosome |
Accession | NZ_CP097107 | ||
Organism | Citrobacter freundii strain GMU8049 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | A0A0J1MPQ6 |
Locus tag | M3L74_RS00345 | Protein ID | WP_003837806.1 |
Coordinates | 6850..7125 (+) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | A0A0J1MMS0 |
Locus tag | M3L74_RS00350 | Protein ID | WP_003837808.1 |
Coordinates | 7122..7481 (+) | Length | 120 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M3L74_RS00335 (2901) | 2901..5648 | + | 2748 | WP_003846160.1 | ribosome-associated ATPase/putative transporter RbbA | - |
M3L74_RS00340 (5648) | 5648..6772 | + | 1125 | WP_003837801.1 | ABC transporter permease | - |
M3L74_RS00345 (6850) | 6850..7125 | + | 276 | WP_003837806.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
M3L74_RS00350 (7122) | 7122..7481 | + | 360 | WP_003837808.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
M3L74_RS00355 (7594) | 7594..7995 | - | 402 | WP_003023387.1 | nickel-responsive transcriptional regulator NikR | - |
M3L74_RS00360 (8045) | 8045..8623 | - | 579 | WP_003023390.1 | 4'-phosphopantetheinyl transferase AcpT | - |
M3L74_RS00365 (8686) | 8686..9735 | - | 1050 | WP_003023393.1 | AI-2E family transporter | - |
M3L74_RS00370 (9869) | 9869..11086 | + | 1218 | WP_103798319.1 | MFS transporter | - |
M3L74_RS00375 (11090) | 11090..11647 | - | 558 | WP_003837816.1 | DcrB family lipoprotein | - |
M3L74_RS00380 (11720) | 11720..12385 | - | 666 | WP_003837818.1 | 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0J1MPQ6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0J1MMS0 |