Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 334011..334565 Replicon chromosome
Accession NZ_CP097103
Organism Pseudomonas sp. NY11382

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag M2J80_RS01505 Protein ID WP_255326884.1
Coordinates 334011..334253 (+) Length 81 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M2J80_RS01510 Protein ID WP_029887656.1
Coordinates 334263..334565 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2J80_RS01485 (M2J80_01480) 329514..330266 - 753 WP_110678165.1 ABC transporter substrate-binding protein -
M2J80_RS01490 (M2J80_01485) 330278..331051 - 774 WP_009682872.1 ABC transporter ATP-binding protein -
M2J80_RS01495 (M2J80_01490) 331693..333078 + 1386 WP_029887657.1 GABA permease -
M2J80_RS01500 (M2J80_01495) 333356..333796 - 441 WP_009682874.1 hypothetical protein -
M2J80_RS01505 (M2J80_01500) 334011..334253 + 243 WP_255326884.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M2J80_RS01510 (M2J80_01505) 334263..334565 + 303 WP_029887656.1 putative addiction module antidote protein Antitoxin
M2J80_RS01520 (M2J80_01515) 334867..335139 - 273 WP_009682876.1 oxidative damage protection protein -
M2J80_RS01525 (M2J80_01520) 335139..336203 - 1065 WP_009682877.1 A/G-specific adenine glycosylase -
M2J80_RS01530 (M2J80_01525) 336200..338446 - 2247 WP_161891597.1 AsmA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 287984..341569 53585


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-80)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-90)


Sequences

Toxin        


Download         Length: 81 a.a.        Molecular weight: 8946.40 Da        Isoelectric Point: 10.5072

>T244778 WP_255326884.1 NZ_CP097103:334011-334253 [Pseudomonas sp. NY11382]
MRDPRAKARINARLRRLELGVKGDCKPVAEGVSELRVDYGPGYRVYFVQRGYEVIILLAGGDKSSQARDIKSALKLARDL

Download         Length: 243 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10748.47 Da        Isoelectric Point: 5.1131

>AT244778 WP_029887656.1 NZ_CP097103:334263-334565 [Pseudomonas sp. NY11382]
MTNIKLTKWDAVDHLKTEEDMALYLEACLEENDPALLAAALGDIARARGMAQLARDTGLTREGLYKALSAEGNPSLATIM
KVMAALGVRLHAEVLPRSVG

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References