Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 2457072..2457619 Replicon chromosome
Accession NZ_CP097102
Organism Halomonas venusta strain SND-01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M3L73_RS12030 Protein ID WP_146945458.1
Coordinates 2457072..2457374 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M3L73_RS12035 Protein ID WP_125748707.1
Coordinates 2457362..2457619 (-) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3L73_RS12000 (M3L73_12000) 2452709..2453197 - 489 WP_125748685.1 VOC family protein -
M3L73_RS12005 (M3L73_12005) 2453321..2454112 - 792 WP_125748688.1 type I methionyl aminopeptidase -
M3L73_RS12010 (M3L73_12010) 2454105..2454311 - 207 WP_125748691.1 ParD-like family protein -
M3L73_RS12015 (M3L73_12015) 2454489..2455703 - 1215 WP_249016631.1 crosslink repair DNA glycosylase YcaQ family protein -
M3L73_RS12020 (M3L73_12020) 2455795..2456199 - 405 WP_146943706.1 DUF1801 domain-containing protein -
M3L73_RS12025 (M3L73_12025) 2456282..2456869 - 588 WP_198350352.1 class I SAM-dependent methyltransferase -
M3L73_RS12030 (M3L73_12030) 2457072..2457374 - 303 WP_146945458.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M3L73_RS12035 (M3L73_12035) 2457362..2457619 - 258 WP_125748707.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
M3L73_RS12040 (M3L73_12040) 2457798..2457884 - 87 Protein_2352 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family -
M3L73_RS12045 (M3L73_12045) 2457990..2458811 + 822 WP_249018217.1 aldo/keto reductase -
M3L73_RS12050 (M3L73_12050) 2458990..2459673 - 684 WP_249016632.1 EamA family transporter -
M3L73_RS12055 (M3L73_12055) 2459670..2459894 - 225 WP_249016633.1 EamA family transporter -
M3L73_RS12060 (M3L73_12060) 2460063..2460944 + 882 WP_022520598.1 helix-turn-helix domain-containing protein -
M3L73_RS12065 (M3L73_12065) 2461090..2461275 - 186 WP_249016634.1 hypothetical protein -
M3L73_RS12070 (M3L73_12070) 2461352..2461546 - 195 WP_249016635.1 hypothetical protein -
M3L73_RS12075 (M3L73_12075) 2461534..2461821 - 288 WP_249016636.1 hypothetical protein -
M3L73_RS12080 (M3L73_12080) 2461888..2462163 - 276 WP_249016637.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 11649.34 Da        Isoelectric Point: 4.4400

>T244777 WP_146945458.1 NZ_CP097102:c2457374-2457072 [Halomonas venusta]
MAEVIWTEPALQELDAIAEYIALDNPAAASHLVQDVFDKTERLENFPRSGRIPPELPNSVYREIVVPPCRIFYREDEKQV
LILYVMREERQLRAYMLGNS

Download         Length: 303 bp


Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9871.46 Da        Isoelectric Point: 9.5103

>AT244777 WP_125748707.1 NZ_CP097102:c2457619-2457362 [Halomonas venusta]
MKVELVTNLKRQATKILADLHLSKEPVLITEHGKPSAYLVDVQDYEFMQRRLELLEGLARGERAVLEGRTYSQSEAREKM
SKWLK

Download         Length: 258 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References