Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1896369..1896514 Replicon chromosome
Accession NZ_CP097079
Organism Klebsiella pneumoniae strain KP131

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1896405..1896507 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1896369..1896514 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3I83_RS09065 1891499..1893559 + 2061 WP_119186028.1 oligopeptidase B -
M3I83_RS09070 1893563..1894222 - 660 WP_119186029.1 exodeoxyribonuclease X -
M3I83_RS09075 1894301..1894531 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M3I83_RS09080 1894644..1895018 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M3I83_RS09085 1895022..1895891 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
M3I83_RS09090 1895908..1896246 + 339 WP_016529031.1 YebY family protein -
- 1896369..1896514 - 146 - - Antitoxin
- 1896405..1896507 + 103 - - Toxin
M3I83_RS09095 1896882..1897025 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M3I83_RS09100 1897130..1898098 - 969 WP_004151446.1 VirK/YbjX family protein -
M3I83_RS09105 1898255..1898908 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
M3I83_RS09110 1898905..1899096 - 192 WP_002911395.1 YebW family protein -
M3I83_RS09115 1899194..1899433 - 240 WP_002911393.1 YebV family protein -
M3I83_RS09120 1899549..1900982 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T244734 NZ_CP097079:1896405-1896507 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT244734 NZ_CP097079:c1896514-1896369 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References