Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2745871..2746501 Replicon chromosome
Accession NZ_CP096972
Organism Sphingomonas sp. SUN039

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag M0209_RS13405 Protein ID WP_258888770.1
Coordinates 2745871..2746236 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag M0209_RS13410 Protein ID WP_258888771.1
Coordinates 2746217..2746501 (+) Length 95 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0209_RS13385 (M0209_13365) 2741573..2742082 - 510 WP_258888766.1 hypothetical protein -
M0209_RS13390 (M0209_13370) 2742082..2742483 - 402 WP_258888767.1 VOC family protein -
M0209_RS13395 (M0209_13375) 2742642..2743583 + 942 WP_258888768.1 SMI1/KNR4 family protein -
M0209_RS13400 (M0209_13380) 2743614..2745803 + 2190 WP_258888769.1 excinuclease ABC subunit UvrB -
M0209_RS13405 (M0209_13385) 2745871..2746236 + 366 WP_258888770.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M0209_RS13410 (M0209_13390) 2746217..2746501 + 285 WP_258888771.1 putative addiction module antidote protein Antitoxin
M0209_RS13415 (M0209_13395) 2746558..2747244 + 687 WP_258888772.1 2OG-Fe(II) oxygenase -
M0209_RS13420 (M0209_13400) 2747270..2747767 - 498 WP_258888773.1 hypothetical protein -
M0209_RS13425 (M0209_13405) 2747819..2748397 - 579 WP_258888774.1 SURF1 family protein -
M0209_RS13430 (M0209_13410) 2748448..2748813 - 366 WP_258888775.1 DUF983 domain-containing protein -
M0209_RS13435 (M0209_13415) 2748823..2749326 - 504 WP_258888776.1 DUF3291 domain-containing protein -
M0209_RS13440 (M0209_13420) 2749327..2750211 - 885 WP_258888777.1 cytochrome c oxidase subunit 3 -
M0209_RS13445 (M0209_13425) 2750254..2750793 - 540 WP_258888778.1 cytochrome c oxidase assembly protein -
M0209_RS13450 (M0209_13430) 2750793..2750933 - 141 WP_258888779.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(19-110)

Antitoxin

(19-92)


Sequences


Toxin        


Download         Length: 122 a.a.        Molecular weight: 13446.37 Da        Isoelectric Point: 9.0687

>T244303 WP_258888770.1 NZ_CP096972:2745871-2746236 [Sphingomonas sp. SUN039]
MAFDVDAMTNVLYEGHKFRVAQTAAFSEWLPLLRDRRALAKITDRLLRAADGNFGDVKSAGSGISEMRIDYGPGYRVYFC
QRGTEIVILLCGGGKRTQQRDIANAKRLKAEIEFSDGTSPL

Download         Length: 366 bp


Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10165.54 Da        Isoelectric Point: 4.4488

>AT244303 WP_258888771.1 NZ_CP096972:2746217-2746501 [Sphingomonas sp. SUN039]
MELRPFDPANYLESGEDILYFLEAAMEGNDPTHIARALGVVARSKGMTEISRKTGLGRQALYTALSEDGNPTLETLTAVL
GALDLELTVQKRAA

Download         Length: 285 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References