244302

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 2052228..2052886 Replicon chromosome
Accession NZ_CP096972
Organism Sphingomonas sp. SUN039

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M0209_RS09995 Protein ID WP_258888129.1
Coordinates 2052228..2052659 (-) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M0209_RS10000 Protein ID WP_258888130.1
Coordinates 2052656..2052886 (-) Length 77 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0209_RS09980 (M0209_09965) 2047934..2049901 + 1968 WP_258888127.1 ATP-binding protein -
M0209_RS09985 (M0209_09970) 2049939..2051132 + 1194 WP_258888128.1 LPS export ABC transporter permease LptF -
M0209_RS09990 (M0209_09975) 2051129..2052226 + 1098 WP_258889614.1 LPS export ABC transporter permease LptG -
M0209_RS09995 (M0209_09980) 2052228..2052659 - 432 WP_258888129.1 PIN domain-containing protein Toxin
M0209_RS10000 (M0209_09985) 2052656..2052886 - 231 WP_258888130.1 hypothetical protein Antitoxin
M0209_RS10005 (M0209_09990) 2052931..2054043 - 1113 WP_258888131.1 fatty acid desaturase -
M0209_RS10010 (M0209_09995) 2054066..2055298 + 1233 WP_258888132.1 N-acetyltransferase -
M0209_RS10015 (M0209_10000) 2055300..2056055 + 756 WP_258888133.1 isocitrate lyase/phosphoenolpyruvate mutase family protein -
M0209_RS10020 (M0209_10005) 2056052..2056276 - 225 WP_258888134.1 hypothetical protein -
M0209_RS10025 (M0209_10010) 2056303..2057073 - 771 WP_258889615.1 exodeoxyribonuclease III -
M0209_RS10030 (M0209_10015) 2057073..2057399 - 327 WP_258888135.1 iron-sulfur cluster insertion protein ErpA -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-127)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 144 a.a.        Molecular weight: 15925.04 Da        Isoelectric Point: 6.3969

>T244302 WP_258888129.1 NZ_CP096972:c2052659-2052228 [Sphingomonas sp. SUN039]
MSRALLDVNVLLALLDPMHIDHERAQDWFADARFDGWATCPITQNGYLRIATQPGYTNPVSVADAIDLLDHFTSQSAHEF
WPASGSLLDRAFCDVLKIPSHRHMTDTYLLALARHHGGRLATLDRRLNINAVAEGSQHLTIIG

Download         Length: 432 bp


Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8336.56 Da        Isoelectric Point: 8.8935

>AT244302 WP_258888130.1 NZ_CP096972:c2052886-2052656 [Sphingomonas sp. SUN039]
MRTTVSIDDDVLEVAKSVAEADRRTIGQVLSDFARKGMAPEPQTAQFRNGIKLMPVRPGAGRATLALVNRLRDEVE

Download         Length: 231 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References