244300

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 786911..787485 Replicon chromosome
Accession NZ_CP096972
Organism Sphingomonas sp. SUN039

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M0209_RS03925 Protein ID WP_258886998.1
Coordinates 787117..787485 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M0209_RS03920 Protein ID WP_258886997.1
Coordinates 786911..787120 (+) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0209_RS03890 (M0209_03880) 782046..782783 - 738 WP_258886991.1 tRNA pseudouridine(38-40) synthase TruA -
M0209_RS03895 (M0209_03885) 782793..783692 - 900 WP_258886992.1 methionyl-tRNA formyltransferase -
M0209_RS03900 (M0209_03890) 783806..784402 + 597 WP_258886993.1 recombination mediator RecR -
M0209_RS03905 (M0209_03895) 784418..784777 + 360 WP_258886994.1 VOC family protein -
M0209_RS03910 (M0209_03900) 784810..785346 + 537 WP_258886995.1 peptide deformylase -
M0209_RS03915 (M0209_03905) 785514..786911 + 1398 WP_258886996.1 DNA recombination protein RmuC -
M0209_RS03920 (M0209_03910) 786911..787120 + 210 WP_258886997.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
M0209_RS03925 (M0209_03915) 787117..787485 + 369 WP_258886998.1 type II toxin-antitoxin system VapC family toxin Toxin
M0209_RS03930 (M0209_03920) 787459..788268 - 810 WP_258886999.1 RNA methyltransferase -
M0209_RS03935 (M0209_03925) 788273..788539 - 267 WP_258887000.1 HPr family phosphocarrier protein -
M0209_RS03940 (M0209_03930) 788536..788955 - 420 WP_258887001.1 PTS sugar transporter subunit IIA -
M0209_RS03945 (M0209_03935) 788952..789893 - 942 WP_258887002.1 RNase adapter RapZ -
M0209_RS03950 (M0209_03940) 789890..790327 - 438 WP_258889554.1 HPr kinase/phosphatase C-terminal domain-containing protein -
M0209_RS03955 (M0209_03945) 790345..791874 - 1530 WP_258887003.1 sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-46)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13169.24 Da        Isoelectric Point: 4.8261

>T244300 WP_258886998.1 NZ_CP096972:787117-787485 [Sphingomonas sp. SUN039]
MILADTCIWADYIDRGDYSLAALLENGAVVTHPFVVAEVLLGNLADRKMWKDQLARLPEFLPVRHSDVMALIDAAELGGS
GVGYVDAHLLAAVLARPGTAIWTRDKKLNRVAGELGVAFEPA

Download         Length: 369 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7629.68 Da        Isoelectric Point: 8.9991

>AT244300 WP_258886997.1 NZ_CP096972:786911-787120 [Sphingomonas sp. SUN039]
MRTTIKIDDELLADAREFSGIDETSALVRHALKTVVQLEAGRRLARLGGSQPGFVAAPRRRPPEFTNPE

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References