Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 360749..361193 Replicon chromosome
Accession NZ_CP096972
Organism Sphingomonas sp. SUN039

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M0209_RS01800 Protein ID WP_258886496.1
Coordinates 360749..361024 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M0209_RS01805 Protein ID WP_258886498.1
Coordinates 361017..361193 (-) Length 59 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0209_RS01770 (M0209_01760) 355866..356072 + 207 WP_258886482.1 HigA family addiction module antitoxin -
M0209_RS01775 (M0209_01765) 356077..356733 - 657 WP_258886484.1 hypothetical protein -
M0209_RS01780 (M0209_01770) 356753..357121 - 369 WP_258886486.1 helix-turn-helix domain-containing protein -
M0209_RS01785 (M0209_01775) 357118..357468 - 351 WP_258886487.1 DUF6516 family protein -
M0209_RS01790 (M0209_01780) 357497..359791 - 2295 WP_258886489.1 UvrD-helicase domain-containing protein -
M0209_RS01795 (M0209_01785) 359802..360728 - 927 WP_258886494.1 DMT family transporter -
M0209_RS01800 (M0209_01790) 360749..361024 - 276 WP_258886496.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M0209_RS01805 (M0209_01795) 361017..361193 - 177 WP_258886498.1 stability determinant Antitoxin
M0209_RS01810 (M0209_01800) 361222..362481 + 1260 WP_258886500.1 MFS transporter -
M0209_RS01815 (M0209_01805) 362471..362926 + 456 WP_258886502.1 GNAT family N-acetyltransferase -
M0209_RS01820 (M0209_01810) 362917..363465 - 549 WP_258886508.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
M0209_RS01825 (M0209_01815) 363801..364505 - 705 Protein_354 rRNA pseudouridine synthase -
M0209_RS01830 (M0209_01820) 364529..365698 - 1170 WP_258889537.1 aromatic ring-hydroxylating dioxygenase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10617.26 Da        Isoelectric Point: 6.9773

>T244299 WP_258886496.1 NZ_CP096972:c361024-360749 [Sphingomonas sp. SUN039]
MLELVWEPLATEQLSAIIEYIAQHNFPAAERLERQIHAKVELACHVPGMGRPGRVSETREIVAHPNYLVIYRVTDERLYV
IRVLHSRQQYP

Download         Length: 276 bp

Antitoxin


Download         Length: 59 a.a.        Molecular weight: 6579.41 Da        Isoelectric Point: 4.7205

>AT244299 WP_258886498.1 NZ_CP096972:c361193-361017 [Sphingomonas sp. SUN039]
MAKLDPIVSEFDTEEDAEAYDKWFRAQVEAGLASKGPWIPHAEVKARTKAILDKYRDA

Download         Length: 177 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References