Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3153153..3153811 Replicon chromosome
Accession NZ_CP096971
Organism Sphingomonas sp. SUN019

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M0208_RS15185 Protein ID WP_258892511.1
Coordinates 3153153..3153548 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M0208_RS15190 Protein ID WP_258892512.1
Coordinates 3153545..3153811 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0208_RS15160 (M0208_15130) 3148481..3149473 - 993 WP_258892506.1 aldo/keto reductase -
M0208_RS15165 (M0208_15135) 3149470..3150738 - 1269 WP_258892507.1 dicarboxylate/amino acid:cation symporter -
M0208_RS15170 (M0208_15140) 3150820..3152160 + 1341 WP_258892508.1 phosphoglucosamine mutase -
M0208_RS15175 (M0208_15145) 3152224..3152607 - 384 WP_258892509.1 hypothetical protein -
M0208_RS15180 (M0208_15150) 3152668..3153156 - 489 WP_258892510.1 DNA-deoxyinosine glycosylase -
M0208_RS15185 (M0208_15155) 3153153..3153548 - 396 WP_258892511.1 type II toxin-antitoxin system VapC family toxin Toxin
M0208_RS15190 (M0208_15160) 3153545..3153811 - 267 WP_258892512.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
M0208_RS15195 (M0208_15165) 3153913..3154893 + 981 WP_258892513.1 cysteine synthase A -
M0208_RS15200 (M0208_15170) 3154941..3155240 + 300 WP_258892514.1 hypothetical protein -
M0208_RS15205 (M0208_15175) 3155551..3156051 + 501 WP_258892515.1 division/cell wall cluster transcriptional repressor MraZ -
M0208_RS15210 (M0208_15180) 3156048..3157019 + 972 WP_258892516.1 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH -
M0208_RS15215 (M0208_15185) 3157016..3157654 + 639 WP_258892517.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-125)

Antitoxin

Antitoxin VapB-like

(5-87)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14378.42 Da        Isoelectric Point: 4.4687

>T244298 WP_258892511.1 NZ_CP096971:c3153548-3153153 [Sphingomonas sp. SUN019]
MIVDTSALMAIILGEPERDLFIAILASADTLSISAGSWVELGAVIVRRQQHMLEHELLALRDDFEFGVEPVTVIQADLAR
VAYREYGRGTGHPAKLNFGDCFAYALARETGEPLLFKGNDFSQTDINPAVK

Download         Length: 396 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9949.36 Da        Isoelectric Point: 7.2053

>AT244298 WP_258892512.1 NZ_CP096971:c3153811-3153545 [Sphingomonas sp. SUN019]
MGVQLNIKDPETVRLARELAGDTGRTVTETVRAALQRAHEDRADKIQAKIAKMNAAVDRLRKHLPPEWKGRTSKEIMDEL
YDEDGLPI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References