Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 31091..31761 Replicon chromosome
Accession NZ_CP096971
Organism Sphingomonas sp. SUN019

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M0208_RS00150 Protein ID WP_258889732.1
Coordinates 31345..31761 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M0208_RS00145 Protein ID WP_258889731.1
Coordinates 31091..31348 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0208_RS00115 (M0208_00115) 26099..26578 - 480 WP_258889725.1 50S ribosomal protein L13 -
M0208_RS00120 (M0208_00120) 26710..27750 - 1041 WP_258889726.1 COX15/CtaA family protein -
M0208_RS00125 (M0208_00125) 27851..28231 + 381 WP_258889727.1 MerC domain-containing protein -
M0208_RS00130 (M0208_00130) 28270..28743 + 474 WP_258889728.1 transcriptional repressor -
M0208_RS00135 (M0208_00135) 28798..30717 + 1920 WP_258889729.1 1-deoxy-D-xylulose-5-phosphate synthase -
M0208_RS00140 (M0208_00140) 30728..31048 + 321 WP_258889730.1 hypothetical protein -
M0208_RS00145 (M0208_00145) 31091..31348 + 258 WP_258889731.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
M0208_RS00150 (M0208_00150) 31345..31761 + 417 WP_258889732.1 PIN domain-containing protein Toxin
M0208_RS00155 (M0208_00155) 31751..32422 - 672 WP_258889733.1 alpha/beta hydrolase -
M0208_RS00160 (M0208_00160) 32600..33334 + 735 WP_258889734.1 TlyA family RNA methyltransferase -
M0208_RS00165 (M0208_00165) 33462..33983 + 522 WP_258893127.1 TspO/MBR family protein -
M0208_RS00170 (M0208_00170) 34009..34263 + 255 WP_258889735.1 accessory factor UbiK family protein -
M0208_RS00175 (M0208_00175) 34312..34815 + 504 WP_258889736.1 YbjN domain-containing protein -
M0208_RS00180 (M0208_00180) 34820..35617 + 798 WP_258889737.1 pyrroline-5-carboxylate reductase -
M0208_RS00185 (M0208_00185) 35614..36114 - 501 WP_258889738.1 MarR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-114)

Antitoxin

SpoVT-AbrB domain

(13-47)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15337.56 Da        Isoelectric Point: 4.5984

>T244296 WP_258889732.1 NZ_CP096971:31345-31761 [Sphingomonas sp. SUN019]
MIATFFDSNVILYSTDRDERKAEIADALIGRGGWISVQVLNEIAHVARRKMQLDWDRVTDLIGTITGLTGVIDLTVELHN
LGRRVAERYKFSIYDGMIVAAALIADCDTLYSEDMHDGLVIDGRLRIVNPFAPDALTG

Download         Length: 417 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9459.75 Da        Isoelectric Point: 5.8374

>AT244296 WP_258889731.1 NZ_CP096971:31091-31348 [Sphingomonas sp. SUN019]
MNVYLEAIMQVAKWGNSLAIRIPADVARALNLKEGDDVGVHALSDGEVAIVTEQQRRGALMERLKSFRGSLPADYKFDRE
EANSR

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References