Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Acetyltransf_4(toxin) |
Location | 1915540..1917048 | Replicon | chromosome |
Accession | NZ_CP096960 | ||
Organism | Pseudomonas aeruginosa strain NY11254 |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | M2I99_RS08895 | Protein ID | WP_073660237.1 |
Coordinates | 1915540..1916127 (+) | Length | 196 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | A0A1C7C4U7 |
Locus tag | M2I99_RS08900 | Protein ID | WP_003091607.1 |
Coordinates | 1916194..1917048 (+) | Length | 285 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M2I99_RS08890 (M2I99_08880) | 1911795..1915274 | - | 3480 | WP_003091610.1 | PAS domain-containing hybrid sensor histidine kinase/response regulator | - |
M2I99_RS08895 (M2I99_08885) | 1915540..1916127 | + | 588 | WP_073660237.1 | GNAT family protein | Toxin |
M2I99_RS08900 (M2I99_08890) | 1916194..1917048 | + | 855 | WP_003091607.1 | AraC family transcriptional regulator | Antitoxin |
M2I99_RS08905 (M2I99_08895) | 1917145..1919310 | + | 2166 | WP_003091606.1 | TonB-dependent receptor family protein | - |
M2I99_RS08910 (M2I99_08900) | 1919485..1921359 | + | 1875 | WP_003091605.1 | MFS transporter | - |
M2I99_RS08915 (M2I99_08905) | 1921420..1921629 | - | 210 | WP_003091604.1 | cold-shock protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 196 a.a. Molecular weight: 21929.29 Da Isoelectric Point: 9.8676
>T244276 WP_073660237.1 NZ_CP096960:1915540-1916127 [Pseudomonas aeruginosa]
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLVEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLVEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG
Download Length: 588 bp
Antitoxin
Download Length: 285 a.a. Molecular weight: 31895.20 Da Isoelectric Point: 7.5295
>AT244276 WP_003091607.1 NZ_CP096960:1916194-1917048 [Pseudomonas aeruginosa]
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPLGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHGGVPRFADSVIHDQPLARAFVHLHRLLAEHAGSLETQTRWRETMLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEVALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTTYE
VPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPLGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHGGVPRFADSVIHDQPLARAFVHLHRLLAEHAGSLETQTRWRETMLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEVALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTTYE
Download Length: 855 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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