244264

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 4921744..4922352 Replicon chromosome
Accession NZ_CP096956
Organism Pseudomonas aeruginosa strain NY11173

Toxin (Protein)


Gene name PfiT Uniprot ID -
Locus tag M2I96_RS23005 Protein ID WP_016263850.1
Coordinates 4921744..4922091 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID A0A0B0C355
Locus tag M2I96_RS23010 Protein ID WP_003114155.1
Coordinates 4922101..4922352 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2I96_RS22975 (M2I96_22905) 4917163..4917375 + 213 WP_003098360.1 cysteine-rich CWC family protein -
M2I96_RS22980 (M2I96_22910) 4917375..4918067 + 693 WP_003098362.1 16S rRNA pseudouridine(516) synthase -
M2I96_RS22985 (M2I96_22915) 4918203..4919246 + 1044 WP_003098363.1 L,D-transpeptidase -
M2I96_RS22990 (M2I96_22920) 4919326..4920063 + 738 WP_003114158.1 murein L,D-transpeptidase catalytic domain family protein -
M2I96_RS22995 (M2I96_22925) 4920515..4921417 + 903 WP_003123042.1 (R)-3-hydroxydecanoyl-ACP:CoA transacylase -
M2I96_RS23005 (M2I96_22935) 4921744..4922091 - 348 WP_016263850.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M2I96_RS23010 (M2I96_22940) 4922101..4922352 - 252 WP_003114155.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
M2I96_RS23015 (M2I96_22945) 4922566..4923549 - 984 WP_019725833.1 tyrosine-type recombinase/integrase -
M2I96_RS23020 (M2I96_22950) 4923549..4924841 - 1293 WP_003115206.1 hypothetical protein -
M2I96_RS23025 (M2I96_22955) 4925100..4926362 - 1263 WP_019725831.1 zonular occludens toxin domain-containing protein -
M2I96_RS23030 (M2I96_22960) 4926364..4926714 - 351 WP_019725830.1 DUF2523 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage catB7 - 4921744..4943887 22143


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-100)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 13046.85 Da        Isoelectric Point: 4.4212

>T244264 WP_016263850.1 NZ_CP096956:c4922091-4921744 [Pseudomonas aeruginosa]
MSPVVIRFTDTAEQSIEDQVHHLVPFQGEQAAFQSVLSLLDEIEEKISLAPKGYPVSQQASLLGVLSYRELNTGPYRVFY
EFHEEQGEVAVILVLRQKQSVEQQLIRYCLVGPIE

Download         Length: 348 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9442.79 Da        Isoelectric Point: 9.4808

>AT244264 WP_003114155.1 NZ_CP096956:c4922352-4922101 [Pseudomonas aeruginosa]
MRVETISYLKRHAADLDLSEPMVVTQNGVPAYVVESYAERKQRDEAIALVKLLAIGSRQYAEGKHRSVDDLKARLSRRFA
QPE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0B0C355

References