Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/Phd(antitoxin) |
| Location | 1826862..1827409 | Replicon | chromosome |
| Accession | NC_013456 | ||
| Organism | Vibrio sp. Ex25 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | VEA_RS08610 | Protein ID | WP_012841717.1 |
| Coordinates | 1827107..1827409 (+) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A2S9V3C6 |
| Locus tag | VEA_RS08605 | Protein ID | WP_012841716.1 |
| Coordinates | 1826862..1827119 (+) | Length | 86 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| VEA_RS08575 | 1822828..1823265 | + | 438 | WP_041852934.1 | GNAT family N-acetyltransferase | - |
| VEA_RS23325 | 1823280..1823372 | + | 93 | WP_012841713.1 | DUF3265 domain-containing protein | - |
| VEA_RS08580 | 1823405..1823806 | + | 402 | WP_005433790.1 | HIT family protein | - |
| VEA_RS23330 | 1823841..1823933 | + | 93 | WP_074534789.1 | DUF3265 domain-containing protein | - |
| VEA_RS08585 | 1823982..1824617 | + | 636 | WP_006741481.1 | LysE family transporter | - |
| VEA_RS23890 | 1824635..1824760 | + | 126 | Protein_1635 | DUF3265 domain-containing protein | - |
| VEA_RS08590 | 1824771..1825481 | + | 711 | WP_006741482.1 | SEC-C domain-containing protein | - |
| VEA_RS23335 | 1825499..1825588 | + | 90 | WP_081442438.1 | DUF3265 domain-containing protein | - |
| VEA_RS08595 | 1825616..1826089 | + | 474 | WP_012841714.1 | hypothetical protein | - |
| VEA_RS08600 | 1826201..1826383 | + | 183 | WP_012841715.1 | hypothetical protein | - |
| VEA_RS08605 | 1826862..1827119 | + | 258 | WP_012841716.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| VEA_RS08610 | 1827107..1827409 | + | 303 | WP_012841717.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| VEA_RS08615 | 1827588..1828058 | + | 471 | WP_012841718.1 | GNAT family N-acetyltransferase | - |
| VEA_RS23340 | 1828088..1828180 | + | 93 | WP_012841719.1 | DUF3265 domain-containing protein | - |
| VEA_RS08620 | 1828209..1828859 | + | 651 | WP_006741484.1 | hypothetical protein | - |
| VEA_RS08625 | 1828976..1830337 | + | 1362 | WP_006741485.1 | hypothetical protein | - |
| VEA_RS23345 | 1830368..1830460 | + | 93 | WP_010448843.1 | DUF3265 domain-containing protein | - |
| VEA_RS08630 | 1830481..1831119 | + | 639 | WP_006741486.1 | class I SAM-dependent methyltransferase | - |
| VEA_RS23350 | 1831157..1831249 | + | 93 | WP_012841722.1 | DUF3265 domain-containing protein | - |
| VEA_RS23355 | 1831655..1831798 | + | 144 | WP_167310324.1 | DUF3265 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | vxsC / exsA / exsD / vscB / vscC / vscD / vscF / vscG / vscI / vscJ / vscK / vscL / vopS / vopR / vecA / vopQ / vscU / vscT / vscS / vscR / vscQ / vscO / vscN / vopN / tyeA/vcr1 / sycN/vcr2 / vscX / vscY / vcrD / vcrR / vcrG / vcrV / vcrH / vopB / vopD / VP1611 | 1668087..2017340 | 349253 | |
| - | inside | Integron | - | - | 1822828..1842877 | 20049 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11704.57 Da Isoelectric Point: 4.8951
>T24426 WP_012841717.1 NC_013456:1827107-1827409 [Vibrio antiquarius]
MAEIIWTEPALSDLNDIAEYIALENIVAAKQFVQTIFSKVERLETFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLSKQ
MAEIIWTEPALSDLNDIAEYIALENIVAAKQFVQTIFSKVERLETFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLSKQ
Download Length: 303 bp
>T24426 NC_013456:1827107-1827409 [Vibrio antiquarius]
ATGGCTGAAATAATCTGGACTGAGCCGGCACTATCTGACCTCAATGATATCGCTGAATACATAGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTTGTACAAACGATCTTCTCTAAAGTTGAACGCCTAGAAACTTTCCCAGAATCAGGTCGTATTCCGC
CCGAACTAGAACATTTAAGTTATCGTGAAGTTGTCGTTAATCCGTGCCGCGTTTTCTATAAACAAGACGGTGACAAGGTA
TTTATTCTGTTTGTTATGCGAGCAGAGAGAGATTTGCGTAAGTTCTTGTTGAGCAAACAATAA
ATGGCTGAAATAATCTGGACTGAGCCGGCACTATCTGACCTCAATGATATCGCTGAATACATAGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTTGTACAAACGATCTTCTCTAAAGTTGAACGCCTAGAAACTTTCCCAGAATCAGGTCGTATTCCGC
CCGAACTAGAACATTTAAGTTATCGTGAAGTTGTCGTTAATCCGTGCCGCGTTTTCTATAAACAAGACGGTGACAAGGTA
TTTATTCTGTTTGTTATGCGAGCAGAGAGAGATTTGCGTAAGTTCTTGTTGAGCAAACAATAA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9606.10 Da Isoelectric Point: 6.7269
>AT24426 WP_012841716.1 NC_013456:1826862-1827119 [Vibrio antiquarius]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLVILEGIARGERALADGKAVSHDEAKDKM
SKWLK
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLVILEGIARGERALADGKAVSHDEAKDKM
SKWLK
Download Length: 258 bp
>AT24426 NC_013456:1826862-1827119 [Vibrio antiquarius]
ATGAAAGTAGAACTAGTTACATCACTTAAGCGTCAAGCAACTAAGATCCTCGCTGATCTCCACGACACTAAAGAACCGGT
ATTAATTACTGAGCATGGTAAGCCATCAGCGTATCTAGTTGATGTTGATGATTACGAGTTTATGCAAAATCGTTTGGTTA
TTCTGGAGGGTATTGCACGGGGAGAGCGTGCACTAGCTGACGGTAAAGCGGTAAGTCATGATGAAGCCAAGGACAAAATG
TCAAAATGGCTGAAATAA
ATGAAAGTAGAACTAGTTACATCACTTAAGCGTCAAGCAACTAAGATCCTCGCTGATCTCCACGACACTAAAGAACCGGT
ATTAATTACTGAGCATGGTAAGCCATCAGCGTATCTAGTTGATGTTGATGATTACGAGTTTATGCAAAATCGTTTGGTTA
TTCTGGAGGGTATTGCACGGGGAGAGCGTGCACTAGCTGACGGTAAAGCGGTAAGTCATGATGAAGCCAAGGACAAAATG
TCAAAATGGCTGAAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|