244208

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 2774662..2775920 Replicon chromosome
Accession NZ_CP096934
Organism Pseudomonas aeruginosa strain NY5511

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag M2I85_RS13430 Protein ID WP_023109087.1
Coordinates 2775165..2775920 (+) Length 252 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID V6AJU7
Locus tag M2I85_RS13425 Protein ID WP_003086329.1
Coordinates 2774662..2775030 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2I85_RS13405 (M2I85_13390) 2770825..2771100 + 276 WP_023088486.1 zinc ribbon domain-containing protein -
M2I85_RS13410 (M2I85_13395) 2771103..2771579 - 477 WP_004353334.1 elongation factor GreAB -
M2I85_RS13415 (M2I85_13400) 2771754..2773247 + 1494 WP_015648322.1 aldehyde dehydrogenase family protein -
M2I85_RS13420 (M2I85_13405) 2773303..2774589 + 1287 WP_054376095.1 FAD-binding oxidoreductase -
M2I85_RS13425 (M2I85_13410) 2774662..2775030 + 369 WP_003086329.1 DUF2384 domain-containing protein Antitoxin
M2I85_RS13430 (M2I85_13415) 2775165..2775920 + 756 WP_023109087.1 RES family NAD+ phosphorylase Toxin
M2I85_RS13435 (M2I85_13420) 2776689..2778050 + 1362 WP_003081943.1 DNA recombination protein RmuC -
M2I85_RS13440 (M2I85_13425) 2778205..2780748 - 2544 WP_033876574.1 acyl-homoserine-lactone acylase QuiP -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(63-207)

Antitoxin

Cro/C1-type helix-turn-helix domain

(23-47)


Sequences

Toxin        


Download         Length: 252 a.a.        Molecular weight: 28264.40 Da        Isoelectric Point: 7.7294

>T244208 WP_023109087.1 NZ_CP096934:2775165-2775920 [Pseudomonas aeruginosa]
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGTAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA

Download         Length: 756 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13367.63 Da        Isoelectric Point: 9.9874

>AT244208 WP_003086329.1 NZ_CP096934:2774662-2775030 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB V6AJU7

References