244174

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 4010277..4011160 Replicon chromosome
Accession NZ_CP096920
Organism Pseudomonas putida strain NY4811

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag M2J85_RS18840 Protein ID WP_060537713.1
Coordinates 4010277..4010714 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID I7C3Q7
Locus tag M2J85_RS18845 Protein ID WP_003250525.1
Coordinates 4010711..4011160 (-) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2J85_RS18825 (M2J85_18745) 4006578..4007807 - 1230 WP_003250533.1 acyl-CoA dehydrogenase -
M2J85_RS18830 (M2J85_18750) 4007948..4008871 + 924 WP_004573723.1 LysR family transcriptional regulator -
M2J85_RS18835 (M2J85_18755) 4009065..4010219 + 1155 WP_060537721.1 aminotransferase class V-fold PLP-dependent enzyme -
M2J85_RS18840 (M2J85_18760) 4010277..4010714 - 438 WP_060537713.1 RES family NAD+ phosphorylase Toxin
M2J85_RS18845 (M2J85_18765) 4010711..4011160 - 450 WP_003250525.1 DUF2384 domain-containing protein Antitoxin
M2J85_RS18850 (M2J85_18770) 4011303..4011956 - 654 WP_004573726.1 oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB -
M2J85_RS18855 (M2J85_18775) 4012060..4012983 + 924 WP_004573727.1 LysR family transcriptional regulator -
M2J85_RS18860 (M2J85_18780) 4013032..4013862 + 831 WP_003250518.1 AraC family transcriptional regulator -
M2J85_RS18865 (M2J85_18785) 4013914..4014498 + 585 WP_060537711.1 LysE family transporter -
M2J85_RS18870 (M2J85_18790) 4014538..4015737 - 1200 WP_003250514.1 sugar transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-138)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(33-91)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15956.26 Da        Isoelectric Point: 5.6016

>T244174 WP_060537713.1 NZ_CP096920:c4010714-4010277 [Pseudomonas putida]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTIMRLLRIELPDTVSQAQLPALQ
PGWSAQPELTRTLGNRFLDDGSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF

Download         Length: 438 bp

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 16956.46 Da        Isoelectric Point: 5.7258

>AT244174 WP_003250525.1 NZ_CP096920:c4011160-4010711 [Pseudomonas putida]
MLAEVLRDNGYHEYRARLQALLDIPELASDFEIHTRITDGFAATWLVKLTERGVLTPVERDQIIPLRTLKSRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGYGL

Download         Length: 450 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I7C3Q7

References