244173

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 3199231..3199762 Replicon chromosome
Accession NZ_CP096920
Organism Pseudomonas putida strain NY4811

Toxin (Protein)


Gene name relE Uniprot ID W2D823
Locus tag M2J85_RS14895 Protein ID WP_011282522.1
Coordinates 3199231..3199512 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID W2D9V6
Locus tag M2J85_RS14900 Protein ID WP_020303033.1
Coordinates 3199499..3199762 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2J85_RS14875 (M2J85_14805) 3194710..3195825 - 1116 WP_270103047.1 TniQ family protein -
M2J85_RS14880 (M2J85_14810) 3195822..3195995 - 174 Protein_2916 transposase -
M2J85_RS14885 (M2J85_14815) 3197049..3198674 + 1626 WP_020301382.1 methyl-accepting chemotaxis protein -
M2J85_RS14890 (M2J85_14820) 3198764..3199011 - 248 Protein_2918 hypothetical protein -
M2J85_RS14895 (M2J85_14825) 3199231..3199512 - 282 WP_011282522.1 type II toxin-antitoxin system YafQ family toxin Toxin
M2J85_RS14900 (M2J85_14830) 3199499..3199762 - 264 WP_020303033.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
M2J85_RS14905 (M2J85_14835) 3199933..3200829 - 897 WP_085986662.1 cation transporter -
M2J85_RS14910 (M2J85_14840) 3200927..3201334 + 408 WP_024015046.1 Cd(II)/Pb(II)-responsive transcriptional regulator -
M2J85_RS14915 (M2J85_14845) 3201465..3201812 + 348 WP_024015047.1 DUF3703 domain-containing protein -
M2J85_RS14920 (M2J85_14850) 3201809..3202318 + 510 WP_003452327.1 signal peptidase II -
M2J85_RS14925 (M2J85_14855) 3202318..3203064 + 747 WP_024015048.1 AraC family transcriptional regulator -
M2J85_RS14930 (M2J85_14860) 3203133..3203999 + 867 WP_024015049.1 sterol desaturase family protein -
M2J85_RS14935 (M2J85_14865) 3204302..3204504 + 203 Protein_2927 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3189536..3206377 16841
- flank IS/Tn - - 3194035..3194649 614


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10710.20 Da        Isoelectric Point: 9.6866

>T244173 WP_011282522.1 NZ_CP096920:c3199512-3199231 [Pseudomonas putida]
MRTIEQTSRFKRDYKREAKGPHRQTLASDFIAVVTALANNQPLAEKHRDHALTGDWKDHRDCHIKPDLVLIYRKPDDAVL
QLVRLGSHSELGL

Download         Length: 282 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9471.95 Da        Isoelectric Point: 4.8096

>AT244173 WP_020303033.1 NZ_CP096920:c3199762-3199499 [Pseudomonas putida]
MSANAVVRARIDEHIKEEATVVLAAMGLTVSDAFRIMLTRVAREKALPFEPLIPNATTIEAMKEARRGGLKSFASVEDLM
ADLNADD

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0W0N2T9

Antitoxin

Source ID Structure
AlphaFold DB A0A0W0N2R7

References