Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 278350..279305 Replicon chromosome
Accession NZ_CP096913
Organism Pseudomonas aeruginosa strain NY7610

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag M2J79_RS01285 Protein ID WP_170868735.1
Coordinates 278979..279305 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag M2J79_RS01280 Protein ID WP_023107584.1
Coordinates 278350..278907 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2J79_RS01255 (M2J79_01255) 273407..273694 - 288 WP_003137130.1 hypothetical protein -
M2J79_RS01260 (M2J79_01260) 273786..274262 - 477 WP_003118626.1 MarR family transcriptional regulator -
M2J79_RS01265 (M2J79_01265) 274303..275793 - 1491 WP_003137133.1 UbiD family decarboxylase HudA -
M2J79_RS01270 (M2J79_01270) 275927..276613 - 687 WP_003106170.1 YoaK family protein -
M2J79_RS01275 (M2J79_01275) 276777..277709 - 933 WP_003084116.1 hypothetical protein -
M2J79_RS01280 (M2J79_01280) 278350..278907 + 558 WP_023107584.1 Panacea domain-containing protein Antitoxin
M2J79_RS01285 (M2J79_01285) 278979..279305 + 327 WP_170868735.1 hypothetical protein Toxin
M2J79_RS01295 (M2J79_01295) 280747..282189 - 1443 WP_003133043.1 DUF2875 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(28-138)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12385.38 Da        Isoelectric Point: 9.1081

>T244158 WP_170868735.1 NZ_CP096913:278979-279305 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLRDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Download         Length: 327 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 21377.14 Da        Isoelectric Point: 5.8950

>AT244158 WP_023107584.1 NZ_CP096913:278350-278907 [Pseudomonas aeruginosa]
VIFSEQKVAHMAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAW
ISPLVDHEVRLVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQS
EELAEIKARDLAERRRHGRKLSEFI

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References