Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2146194..2146428 Replicon chromosome
Accession NZ_CP096902
Organism Escherichia coli strain RSHH22

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2146324..2146427 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2146194..2146428 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M1Y13_RS10525 2142749..2143411 - 663 WP_000944256.1 exodeoxyribonuclease X -
M1Y13_RS10530 2143435..2144091 - 657 WP_242386750.1 carbon-nitrogen hydrolase family protein YobB -
M1Y13_RS10535 2144193..2144423 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M1Y13_RS10540 2144562..2144936 + 375 WP_000204699.1 CopC domain-containing protein YobA -
M1Y13_RS10545 2144940..2145812 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
M1Y13_RS10550 2145825..2146166 + 342 WP_000976492.1 YebY family protein -
- 2146194..2146428 - 235 - - Antitoxin
- 2146324..2146427 + 104 - - Toxin
M1Y13_RS10555 2146559..2147635 - 1077 WP_001189091.1 phage integrase Arm DNA-binding domain-containing protein -
M1Y13_RS10560 2147601..2147882 - 282 WP_001311878.1 excisionase -
M1Y13_RS10565 2147989..2148177 - 189 WP_001356607.1 DUF1187 family protein -
- 2147993..2148171 + 179 NuclAT_0 - -
- 2147993..2148171 + 179 NuclAT_0 - -
- 2147993..2148171 + 179 NuclAT_0 - -
- 2147993..2148171 + 179 NuclAT_0 - -
M1Y13_RS10570 2148170..2148364 - 195 WP_129542092.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
M1Y13_RS10575 2148397..2149077 - 681 WP_129541926.1 YqaJ viral recombinase family protein -
M1Y13_RS10580 2149074..2149859 - 786 WP_063119826.1 phage recombination protein Bet -
M1Y13_RS10585 2149865..2150161 - 297 WP_129542093.1 host-nuclease inhibitor Gam family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2124175..2211247 87072


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T244096 NZ_CP096902:2146324-2146427 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT244096 NZ_CP096902:c2146428-2146194 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References