Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3533234..3533887 Replicon chromosome
Accession NZ_CP096894
Organism Acinetobacter baumannii strain Mu1956

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag M1783_RS17050 Protein ID WP_000607077.1
Coordinates 3533234..3533623 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag M1783_RS17055 Protein ID WP_001288210.1
Coordinates 3533630..3533887 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M1783_RS17035 (M1783_17035) 3528352..3530547 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
M1783_RS17040 (M1783_17040) 3530735..3531301 - 567 WP_000651538.1 rhombosortase -
M1783_RS17045 (M1783_17045) 3531379..3532464 - 1086 WP_000049106.1 hypothetical protein -
M1783_RS17050 (M1783_17050) 3533234..3533623 - 390 WP_000607077.1 membrane protein Toxin
M1783_RS17055 (M1783_17055) 3533630..3533887 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
M1783_RS17060 (M1783_17060) 3534075..3535247 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
M1783_RS17065 (M1783_17065) 3535296..3536786 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
M1783_RS17070 (M1783_17070) 3536968..3537345 - 378 WP_001216380.1 50S ribosomal protein L17 -
M1783_RS17075 (M1783_17075) 3537364..3538371 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T244086 WP_000607077.1 NZ_CP096894:c3533623-3533234 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT244086 WP_001288210.1 NZ_CP096894:c3533887-3533630 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References