Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1380428..1381344 Replicon chromosome
Accession NZ_CP096889
Organism Bacillus cabrialesii strain TE3

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag EFK13_RS07175 Protein ID WP_129505965.1
Coordinates 1380598..1381344 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID -
Locus tag EFK13_RS07170 Protein ID WP_064813250.1
Coordinates 1380428..1380598 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EFK13_RS07135 (EFK13_07135) 1377299..1377628 + 330 WP_129505969.1 XkdW family protein -
EFK13_RS07140 (EFK13_07140) 1377625..1377789 + 165 WP_075745568.1 XkdX family protein -
EFK13_RS07145 (EFK13_07145) 1377834..1378676 + 843 WP_129505968.1 phage portal protein -
EFK13_RS07150 (EFK13_07150) 1378726..1378995 + 270 WP_119997125.1 hemolysin XhlA family protein -
EFK13_RS07155 (EFK13_07155) 1379008..1379271 + 264 WP_129505967.1 phage holin -
EFK13_RS07160 (EFK13_07160) 1379284..1380177 + 894 WP_129505966.1 N-acetylmuramoyl-L-alanine amidase -
EFK13_RS07165 (EFK13_07165) 1380205..1380342 - 138 WP_119913750.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISC -
EFK13_RS07170 (EFK13_07170) 1380428..1380598 - 171 WP_064813250.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISB Antitoxin
EFK13_RS07175 (EFK13_07175) 1380598..1381344 - 747 WP_129505965.1 toxin-antitoxin-antitoxin system toxin SpoIISA Toxin
EFK13_RS07180 (EFK13_07180) 1381454..1382455 - 1002 WP_129505964.1 inorganic phosphate transporter -
EFK13_RS07185 (EFK13_07185) 1382468..1383085 - 618 WP_003218470.1 DUF47 domain-containing protein -
EFK13_RS07190 (EFK13_07190) 1383362..1384678 - 1317 WP_129505963.1 serine/threonine exchanger -
EFK13_RS07195 (EFK13_07195) 1385065..1386015 + 951 WP_129505962.1 ring-cleaving dioxygenase -
EFK13_RS07200 (EFK13_07200) 1386093..1386239 + 147 WP_129505961.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1347514..1386015 38501


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 28938.31 Da        Isoelectric Point: 4.4393

>T244084 WP_129505965.1 NZ_CP096889:c1381344-1380598 [Bacillus cabrialesii]
MLLFFQIMVWCIMAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYDPSSLFADWERYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLNRLKTYQYLLKNEPIHVYYGSVDAYAEGIDKLLKTYADKMNLTASL
CHYSTQADKDRLTEHMDDPADVQTRLDRKDVYYDQDGKVVLIPFTIETQSYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6571.59 Da        Isoelectric Point: 10.6955

>AT244084 WP_064813250.1 NZ_CP096889:c1380598-1380428 [Bacillus cabrialesii]
MERAYQNGCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References