Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1206486..1207140 Replicon chromosome
Accession NC_013441
Organism Gordonia bronchialis DSM 43247

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GBRO_RS05640 Protein ID WP_052298363.1
Coordinates 1206486..1206905 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GBRO_RS25110 Protein ID WP_083775533.1
Coordinates 1206895..1207140 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GBRO_RS05630 1204843..1205277 - 435 WP_012833025.1 MarR family transcriptional regulator -
GBRO_RS05635 1205375..1206475 + 1101 WP_012833026.1 epoxide hydrolase -
GBRO_RS05640 1206486..1206905 - 420 WP_052298363.1 PIN domain-containing protein Toxin
GBRO_RS25110 1206895..1207140 - 246 WP_083775533.1 hypothetical protein Antitoxin
GBRO_RS05645 1207175..1208055 - 881 Protein_1120 putative DNA binding domain-containing protein -
GBRO_RS26265 1208180..1208467 - 288 WP_012833029.1 hypothetical protein -
GBRO_RS05655 1208629..1209003 - 375 WP_012833030.1 VOC family protein -
GBRO_RS05660 1209164..1209517 - 354 WP_012833031.1 hypothetical protein -
GBRO_RS05665 1209554..1209847 - 294 WP_012833032.1 hypothetical protein -
GBRO_RS05670 1209856..1210698 + 843 Protein_1125 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15188.41 Da        Isoelectric Point: 6.2135

>T24399 WP_052298363.1 NC_013441:c1206905-1206486 [Gordonia bronchialis DSM 43247]
MLLDINVLVALSWDQHVHHGVAHERFAQLTEWSTCPVTEAGLVRVLMTESAVGRVVTGAEALGQLAALRTVTGWGFLHDD
ASLADSVIDLRVLMGRRQVTDLHLVNLAARNGRKLATFDAGLRESLVPADRAWVEVWSA

Download         Length: 420 bp

>T24399 NC_013441:c1206905-1206486 [Gordonia bronchialis DSM 43247]
ATGCTTCTTGACATCAATGTTCTGGTGGCGCTGTCCTGGGATCAGCACGTCCATCACGGCGTCGCGCACGAGCGATTCGC
TCAGCTGACCGAATGGAGTACCTGTCCGGTCACGGAGGCGGGCCTGGTGCGGGTTCTCATGACCGAGTCGGCCGTCGGCC
GAGTGGTCACCGGGGCCGAGGCGCTCGGTCAGCTCGCAGCGCTGCGTACCGTCACTGGATGGGGTTTCCTCCACGACGAT
GCATCGCTCGCAGACTCGGTGATCGACCTGCGCGTCCTCATGGGACGACGTCAGGTGACCGACCTTCACCTGGTGAATCT
GGCTGCGCGCAATGGCCGGAAGCTGGCGACATTCGATGCCGGGTTGCGTGAATCGCTGGTGCCGGCGGACCGTGCGTGGG
TTGAGGTCTGGAGCGCTTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8087.99 Da        Isoelectric Point: 4.6140

>AT24399 WP_083775533.1 NC_013441:c1207140-1206895 [Gordonia bronchialis DSM 43247]
VRTTLDLDPVVLSAARAKAKADGISLGKAVSELARAGLSAPRSAAATSAPSGFPVLTGVPGHPVTDDAVAEYRDDDVTDA
S

Download         Length: 246 bp

>AT24399 NC_013441:c1207140-1206895 [Gordonia bronchialis DSM 43247]
GTGCGAACCACCCTTGACCTCGACCCCGTGGTCTTGAGTGCTGCCAGGGCGAAGGCCAAGGCAGACGGCATTTCGTTGGG
CAAGGCGGTCTCGGAGTTGGCCCGCGCCGGCCTCAGCGCACCGCGATCCGCGGCAGCCACTTCGGCCCCATCCGGCTTTC
CTGTGCTGACCGGCGTCCCGGGGCATCCGGTGACCGATGATGCGGTCGCCGAGTATCGCGATGATGACGTCACCGATGCT
TCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References