Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 906869..907529 | Replicon | chromosome |
Accession | NC_013421 | ||
Organism | Pectobacterium wasabiae WPP163 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A8B3EZX7 |
Locus tag | PECWA_RS04160 | Protein ID | WP_012822581.1 |
Coordinates | 907116..907529 (+) | Length | 138 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | A0A0H3I0G9 |
Locus tag | PECWA_RS04155 | Protein ID | WP_012822580.1 |
Coordinates | 906869..907135 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PECWA_RS04135 | 902861..903865 | - | 1005 | WP_012822576.1 | substrate-binding domain-containing protein | - |
PECWA_RS04140 | 903919..904527 | - | 609 | WP_012822577.1 | HD domain-containing protein | - |
PECWA_RS04145 | 904938..905585 | + | 648 | WP_012822578.1 | hemolysin III family protein | - |
PECWA_RS04150 | 905640..906641 | - | 1002 | WP_012822579.1 | tRNA-modifying protein YgfZ | - |
PECWA_RS04155 | 906869..907135 | + | 267 | WP_012822580.1 | FAD assembly factor SdhE | Antitoxin |
PECWA_RS04160 | 907116..907529 | + | 414 | WP_012822581.1 | protein YgfX | Toxin |
PECWA_RS04165 | 907755..908690 | + | 936 | WP_012822582.1 | 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF | - |
PECWA_RS04170 | 908778..909101 | - | 324 | WP_012822583.1 | hypothetical protein | - |
PECWA_RS04175 | 909130..909648 | - | 519 | WP_012822584.1 | flavodoxin FldB | - |
PECWA_RS04180 | 909976..910992 | + | 1017 | WP_012822585.1 | methionine ABC transporter ATP-binding protein | - |
PECWA_RS04185 | 910985..911653 | + | 669 | WP_012822586.1 | ABC transporter permease | - |
PECWA_RS04190 | 911671..912489 | + | 819 | WP_025919822.1 | MetQ/NlpA family ABC transporter substrate-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 138 a.a. Molecular weight: 16259.20 Da Isoelectric Point: 10.7923
>T24392 WP_012822581.1 NC_013421:907116-907529 [Pectobacterium parmentieri WPP163]
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGCITLLSETTLNWRQQ
EWRIVKRPWLLKNGVLLALQSANGKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGCITLLSETTLNWRQQ
EWRIVKRPWLLKNGVLLALQSANGKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR
Download Length: 414 bp
>T24392 NC_013421:907116-907529 [Pectobacterium parmentieri WPP163]
GTGGCCCAGTGGCAATGTGACCTTCGCGTTTCCTGGCGCATGCAACTGCTGTCATTGGTTGTGCATGGTCTATTAGTGTT
GCTCATTCTGCTGGCACCGTGGCCGGACGGCTATGCGTGGCTGTGGCTGTGTTTGGTCACAATGGTGATGTTTGGTTTCA
TCCGTAGCCAAAGGAATATCAAATCGCGGCAAGGGTGCATCACGCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAGTGGCGGATTGTCAAACGACCGTGGTTGCTGAAAAATGGTGTGTTATTGGCATTGCAATCGGCTAATGGGAAAGACAA
GCAACAACTGTGGCTGGCATCGGACAGCATGGGCGATGACGAATGGCGTCATCTGCGCCAGCTTCTTTTGCAGCAAAAAC
ACTGGGCGAGATGA
GTGGCCCAGTGGCAATGTGACCTTCGCGTTTCCTGGCGCATGCAACTGCTGTCATTGGTTGTGCATGGTCTATTAGTGTT
GCTCATTCTGCTGGCACCGTGGCCGGACGGCTATGCGTGGCTGTGGCTGTGTTTGGTCACAATGGTGATGTTTGGTTTCA
TCCGTAGCCAAAGGAATATCAAATCGCGGCAAGGGTGCATCACGCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAGTGGCGGATTGTCAAACGACCGTGGTTGCTGAAAAATGGTGTGTTATTGGCATTGCAATCGGCTAATGGGAAAGACAA
GCAACAACTGTGGCTGGCATCGGACAGCATGGGCGATGACGAATGGCGTCATCTGCGCCAGCTTCTTTTGCAGCAAAAAC
ACTGGGCGAGATGA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10519.99 Da Isoelectric Point: 5.1392
>AT24392 WP_012822580.1 NC_013421:906869-907135 [Pectobacterium parmentieri WPP163]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDIDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDIDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM
Download Length: 267 bp
>AT24392 NC_013421:906869-907135 [Pectobacterium parmentieri WPP163]
ATGGAAATCGATAACAAATCACGTATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTGGATATCGCCATCATGCCGTT
TTTTGAGCATGACTATGACACATTAAACGATATAGATAAGCGCACGTTTGTACGCCTGCTACAAAGCGACGATCCCGATT
TATTCAACTGGCTAATGAACCACGGTGAGCCAGAAGACGGAGAGCTAAAACGCATGATTTCCCTTATCCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA
ATGGAAATCGATAACAAATCACGTATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTGGATATCGCCATCATGCCGTT
TTTTGAGCATGACTATGACACATTAAACGATATAGATAAGCGCACGTTTGTACGCCTGCTACAAAGCGACGATCCCGATT
TATTCAACTGGCTAATGAACCACGGTGAGCCAGAAGACGGAGAGCTAAAACGCATGATTTCCCTTATCCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8B3EZX7 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0H3I0G9 |