Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 906869..907529 Replicon chromosome
Accession NC_013421
Organism Pectobacterium wasabiae WPP163

Toxin (Protein)


Gene name cptA Uniprot ID A0A8B3EZX7
Locus tag PECWA_RS04160 Protein ID WP_012822581.1
Coordinates 907116..907529 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A0H3I0G9
Locus tag PECWA_RS04155 Protein ID WP_012822580.1
Coordinates 906869..907135 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PECWA_RS04135 902861..903865 - 1005 WP_012822576.1 substrate-binding domain-containing protein -
PECWA_RS04140 903919..904527 - 609 WP_012822577.1 HD domain-containing protein -
PECWA_RS04145 904938..905585 + 648 WP_012822578.1 hemolysin III family protein -
PECWA_RS04150 905640..906641 - 1002 WP_012822579.1 tRNA-modifying protein YgfZ -
PECWA_RS04155 906869..907135 + 267 WP_012822580.1 FAD assembly factor SdhE Antitoxin
PECWA_RS04160 907116..907529 + 414 WP_012822581.1 protein YgfX Toxin
PECWA_RS04165 907755..908690 + 936 WP_012822582.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
PECWA_RS04170 908778..909101 - 324 WP_012822583.1 hypothetical protein -
PECWA_RS04175 909130..909648 - 519 WP_012822584.1 flavodoxin FldB -
PECWA_RS04180 909976..910992 + 1017 WP_012822585.1 methionine ABC transporter ATP-binding protein -
PECWA_RS04185 910985..911653 + 669 WP_012822586.1 ABC transporter permease -
PECWA_RS04190 911671..912489 + 819 WP_025919822.1 MetQ/NlpA family ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16259.20 Da        Isoelectric Point: 10.7923

>T24392 WP_012822581.1 NC_013421:907116-907529 [Pectobacterium parmentieri WPP163]
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGCITLLSETTLNWRQQ
EWRIVKRPWLLKNGVLLALQSANGKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR

Download         Length: 414 bp

>T24392 NC_013421:907116-907529 [Pectobacterium parmentieri WPP163]
GTGGCCCAGTGGCAATGTGACCTTCGCGTTTCCTGGCGCATGCAACTGCTGTCATTGGTTGTGCATGGTCTATTAGTGTT
GCTCATTCTGCTGGCACCGTGGCCGGACGGCTATGCGTGGCTGTGGCTGTGTTTGGTCACAATGGTGATGTTTGGTTTCA
TCCGTAGCCAAAGGAATATCAAATCGCGGCAAGGGTGCATCACGCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAGTGGCGGATTGTCAAACGACCGTGGTTGCTGAAAAATGGTGTGTTATTGGCATTGCAATCGGCTAATGGGAAAGACAA
GCAACAACTGTGGCTGGCATCGGACAGCATGGGCGATGACGAATGGCGTCATCTGCGCCAGCTTCTTTTGCAGCAAAAAC
ACTGGGCGAGATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10519.99 Da        Isoelectric Point: 5.1392

>AT24392 WP_012822580.1 NC_013421:906869-907135 [Pectobacterium parmentieri WPP163]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDIDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT24392 NC_013421:906869-907135 [Pectobacterium parmentieri WPP163]
ATGGAAATCGATAACAAATCACGTATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTGGATATCGCCATCATGCCGTT
TTTTGAGCATGACTATGACACATTAAACGATATAGATAAGCGCACGTTTGTACGCCTGCTACAAAGCGACGATCCCGATT
TATTCAACTGGCTAATGAACCACGGTGAGCCAGAAGACGGAGAGCTAAAACGCATGATTTCCCTTATCCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A8B3EZX7

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3I0G9

References