Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 549069..549652 Replicon chromosome
Accession NC_013421
Organism Pectobacterium wasabiae WPP163

Toxin (Protein)


Gene name parE Uniprot ID A0A7V8QAI8
Locus tag PECWA_RS02475 Protein ID WP_012822278.1
Coordinates 549347..549652 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7V8TMU0
Locus tag PECWA_RS02470 Protein ID WP_012822277.1
Coordinates 549069..549359 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PECWA_RS02450 544171..545433 - 1263 WP_012822274.1 L-rhamnose isomerase -
PECWA_RS02455 545430..546920 - 1491 WP_012822275.1 rhamnulokinase -
PECWA_RS02460 547289..548128 + 840 WP_005971146.1 HTH-type transcriptional activator RhaS -
PECWA_RS02465 548153..549007 + 855 WP_012822276.1 helix-turn-helix domain-containing protein -
PECWA_RS02470 549069..549359 + 291 WP_012822277.1 ribbon-helix-helix protein, CopG family Antitoxin
PECWA_RS02475 549347..549652 + 306 WP_012822278.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PECWA_RS02480 549712..551400 - 1689 WP_012822279.1 ABC transporter ATP-binding protein -
PECWA_RS02485 551397..552263 - 867 WP_012822280.1 ABC transporter permease -
PECWA_RS02490 552256..553215 - 960 WP_012822281.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-96)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11634.48 Da        Isoelectric Point: 9.4590

>T24391 WP_012822278.1 NC_013421:549347-549652 [Pectobacterium parmentieri WPP163]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTDRVVILTVKHQKEAGYQNP

Download         Length: 306 bp

>T24391 NC_013421:549347-549652 [Pectobacterium parmentieri WPP163]
ATGCCACAAGTGATTGTTTCAGAACGCGCAAGACGTGATTTGCAGCGTCTGCAGGATTTTCTAAAAAACAAAAATGCGCT
GGCTGCGAAAAAGGCCGCTGAAGTTTTGATTCGGGGCATTCGTCAGTTAGAAGCGCTGCCGAATATCGGGCGACCCGTTG
AACATCTCCCTCTTGAATATCAGGAACTGGTGATCGAATTCGGCAGCAGCGGGTACGTGATGCTTTACCGCCATGATGAA
CTGACTGACAGAGTGGTGATCCTGACCGTCAAGCATCAAAAAGAAGCCGGTTACCAAAACCCTTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11097.16 Da        Isoelectric Point: 4.7845

>AT24391 WP_012822277.1 NC_013421:549069-549359 [Pectobacterium parmentieri WPP163]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEEYQNTGEHITADETVTWL
ESWGSGHEQDAPACHK

Download         Length: 291 bp

>AT24391 NC_013421:549069-549359 [Pectobacterium parmentieri WPP163]
ATGGCTGACACGCCACGCCAAACCACGACGCTGCGCATCGATCAGGACATTAAAGAACGACTGAAAACGTTGGCCGATGA
CCGCCATAGCTCAGCCCATGCGCTAATGCTGGAAGCCATCGCCGAATACGTGGAGCGTGAAGAAAAACGCAGTCAGTACC
GTAAAGAGGCGCTGGCCGCGTGGGAGGAATACCAGAACACCGGCGAACACATCACCGCCGATGAGACGGTCACCTGGTTA
GAATCCTGGGGTTCTGGGCATGAACAGGATGCGCCTGCATGCCACAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7V8QAI8

Antitoxin

Source ID Structure
AlphaFold DB A0A7V8TMU0

References