24389

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 354876..355407 Replicon chromosome
Accession NC_013421
Organism Pectobacterium wasabiae WPP163

Toxin (Protein)


Gene name stbE Uniprot ID A0A1V2R9S3
Locus tag PECWA_RS01600 Protein ID WP_012822123.1
Coordinates 355120..355407 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A0H3HYL0
Locus tag PECWA_RS01595 Protein ID WP_012822122.1
Coordinates 354876..355130 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PECWA_RS01580 351488..352375 + 888 WP_012822119.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
PECWA_RS22920 353794..354078 + 285 Protein_310 hypothetical protein -
PECWA_RS01590 354299..354595 + 297 WP_052301439.1 hypothetical protein -
PECWA_RS01595 354876..355130 + 255 WP_012822122.1 plasmid stabilization protein Antitoxin
PECWA_RS01600 355120..355407 + 288 WP_012822123.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PECWA_RS01605 355586..356374 + 789 WP_012822124.1 4,5-DOPA dioxygenase extradiol -
PECWA_RS01610 356462..357622 - 1161 WP_012822125.1 glutathionylspermidine synthase family protein -
PECWA_RS01615 357634..358302 - 669 WP_012822126.1 DUF1190 family protein -
PECWA_RS01620 358585..359976 - 1392 WP_012822127.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10997.94 Da        Isoelectric Point: 10.7694

>T24389 WP_012822123.1 NC_013421:355120-355407 [Pectobacterium parmentieri WPP163]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQVYSDTKGRSA

Download         Length: 288 bp

>T24389 NC_013421:355120-355407 [Pectobacterium parmentieri WPP163]
ATGACCTATAAGTTAAAATTTGTGCCTTCTGCAATGAAGGAATGGAAAAAATTAGGGCATCCTGTCAGGGAACAATTCAA
AAAAAAGCTAGTTGAGCGTTTAGAAAATCCTCGCGTTCCTTCAGCCCAGCTTCATGGTCGTAAAGACCAGTATAAAATTA
AACTGAAGTCTGCTGGTTACAGGCTGGTGTATTTGGTTCAGGATGAGACCATTACGGTGATGGTCATGGGGGTTGGAAAG
CGCGAAGGTAGTCAGGTTTATTCTGATACTAAAGGTCGCTCTGCTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9237.47 Da        Isoelectric Point: 3.9490

>AT24389 WP_012822122.1 NC_013421:354876-355130 [Pectobacterium parmentieri WPP163]
MAFNILTNTAASITELKRDPMGTVRSAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDERMSEIADAKEIS
LDDL

Download         Length: 255 bp

>AT24389 NC_013421:354876-355130 [Pectobacterium parmentieri WPP163]
ATGGCTTTCAATATTCTAACTAACACAGCAGCCAGTATCACTGAGTTGAAACGTGACCCAATGGGGACGGTGCGCTCTGC
TGAAGGTGAAACTATCGCTATACTGAACCGCAATGAGCCTGCGTTCTATTGCGTGCCTCCTGCTGTGTTCGCTTACTTGA
TGGAACTCGCTGAAGATGCAGAATTGGGGCGTACCGTTGATGAGCGGATGTCAGAGATAGCTGATGCGAAAGAGATTTCG
CTCGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1V2R9S3

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3HYL0

References