Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2345571..2345842 Replicon chromosome
Accession NC_013364
Organism Escherichia coli O111:H- str. 11128

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2345609..2345712 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2345571..2345842 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECO111_RS12265 2342728..2344167 + 1440 WP_000057021.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ECO111_RS12270 2344285..2344521 + 237 WP_001295499.1 DUF1480 family protein -
ECO111_RS12275 2344626..2344817 + 192 WP_001296140.1 YebW family protein -
ECO111_RS12280 2344818..2345474 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2345571..2345842 + 272 - - Antitoxin
- 2345609..2345712 - 104 - - Toxin
ECO111_RS12290 2345870..2346211 - 342 WP_000976492.1 YebY family protein -
ECO111_RS12295 2346224..2347096 - 873 WP_000879274.1 copper homeostasis membrane protein CopD -
ECO111_RS12300 2347100..2347474 - 375 WP_000204699.1 CopC domain-containing protein YobA -
ECO111_RS12305 2347613..2347843 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ECO111_RS12310 2347945..2348601 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
ECO111_RS12315 2348625..2349287 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T24352 NC_013364:c2345712-2345609 [Escherichia coli O111:H- str. 11128]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT24352 NC_013364:2345571-2345842 [Escherichia coli O111:H- str. 11128]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References