Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 4265674..4267372 Replicon chromosome
Accession NZ_CP096821
Organism Pectobacterium sp. 21LCBS03

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag MYB54_RS18960 Protein ID WP_014914053.1
Coordinates 4266443..4267372 (+) Length 310 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag MYB54_RS18955 Protein ID WP_014914054.1
Coordinates 4265674..4266456 (+) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MYB54_RS18920 (MYB54_18920) 4260864..4262594 + 1731 WP_248721203.1 protein-disulfide reductase DsbD -
MYB54_RS18925 (MYB54_18925) 4262629..4263204 + 576 WP_014914059.1 transcriptional regulator -
MYB54_RS18930 (MYB54_18930) 4263201..4263791 - 591 WP_043901803.1 LysE family translocator -
MYB54_RS18935 (MYB54_18935) 4263827..4264672 - 846 WP_014914057.1 AraC family transcriptional regulator -
MYB54_RS18945 (MYB54_18945) 4265153..4265362 - 210 WP_014914056.1 helix-turn-helix transcriptional regulator -
MYB54_RS18950 (MYB54_18950) 4265359..4265496 - 138 WP_187290706.1 hypothetical protein -
MYB54_RS18955 (MYB54_18955) 4265674..4266456 + 783 WP_014914054.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
MYB54_RS18960 (MYB54_18960) 4266443..4267372 + 930 WP_014914053.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
MYB54_RS18965 (MYB54_18965) 4267755..4268657 - 903 WP_248721204.1 LysR family transcriptional regulator -
MYB54_RS18970 (MYB54_18970) 4268786..4269049 + 264 WP_012773200.1 DUF2798 domain-containing protein -
MYB54_RS18975 (MYB54_18975) 4269131..4269916 - 786 WP_014914051.1 phosphonate metabolism protein PhnP -
MYB54_RS18980 (MYB54_18980) 4269955..4270524 - 570 WP_043901802.1 ribose 1,5-bisphosphokinase -
MYB54_RS18985 (MYB54_18985) 4270527..4271663 - 1137 WP_248721205.1 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-261)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(2-92)


Sequences

Toxin        


Download         Length: 310 a.a.        Molecular weight: 35079.40 Da        Isoelectric Point: 5.6727

>T243418 WP_014914053.1 NZ_CP096821:4266443-4267372 [Pectobacterium sp. 21LCBS03]
MDQRDIYARQVKLLMTSLPYVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIGIDDALMRITESLNGR
QGITAIQQENKADEKRIIVNTADAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEYGFTTMSVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPCMTREIFDGFLCYLAGHPRPIAELLAPNWDTSRIATLYAQEFSGMTQQETSLESLLSVATLLPQAL
KSHFTAQDRQFLLSYKQNNPDWSLYRYPDIQHLPAIRWKQRNLSALHAKNPAKFSAAVGKLEKVLEQHF

Download         Length: 930 bp

>T243418 NZ_OX336253:c2324165-2323989 [Neisseria sp. Marseille-Q5346]
ATGAAGCAGAGCGAATTTTTAAAATGGCTGATGGCACAAGGCGTTGAAACCAAAGACGGTACGCGGCACATCAAGCTGTA
TTACAAGGGCAAGCAGTCGCATCTGCCCCGCCACCCGTCCAAAGAGCTGAAAACGGGCTTGGTCGAAGGAATCAAAAAAC
AGCTCGGTTTAAAATAA

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29271.55 Da        Isoelectric Point: 9.0909

>AT243418 WP_014914054.1 NZ_CP096821:4265674-4266456 [Pectobacterium sp. 21LCBS03]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQIWLTLPAYIKLPGWFTAFKPSATFVVLYTSGLSVDVMPFTTELRIGDRRLTGSVPELAAYEIA
SGVPAQISFEHADALFQGLNLLSPRKLQALLSASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIIPGGWLEP
DYQITVPREFKSEGVEDGSA

Download         Length: 783 bp

>AT243418 NZ_OX336253:c2323952-2323536 [Neisseria sp. Marseille-Q5346]
ATGTACTATCCCGCAAAATTTACCCCCGCCGAGGAAGGCGGCTATGTCGTTACCTTCCGCGATATTCCCGAAGCCATTAC
GCAGGGCGACGACATGACCGAAGCGGTCGAAATGGCGGAAGACGTGTTGCAGTCCGCAATGGATTTCTATTTTGAAGACC
AACGCCCCGCACCCTTGCCGTCCGCCCCCGAAGAAGGCGAACGCTTGGTCGCGCTGCCCTTGTCGGTTTATTCGAAAGTA
TTGCTGCTCAATGAAATGCTGGCGCAGGACGTAAGCAAATCGGAACTAGCAAGGCGTCTGGAAACCACGCCGCAAGAGGT
TCAGCGGATTACCGGCTTGCACCACGCCACCAAAATCGATACGGTCGTCCGCGCTTTGGCGCAACTGGGCAAACAGCTTG
AAATCCGCCTTGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References