Detailed information of TA system TA243409

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 466178..466831
• Replicon: chromosome
• Accession: NZ_CP096818
• Organism: Acinetobacter baumannii strain Mu1984

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: M1R67_RS02265
• Protein ID: WP_000607077.1
• Coordinates: 466442..466831 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: M1R67_RS02260
• Protein ID: WP_001288210.1
• Coordinates: 466178..466435 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M1R67_RS02240 (M1R67_02240)	461694..462701	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
M1R67_RS02245 (M1R67_02245)	462720..463097	+	378	WP_001216380.1	50S ribosomal protein L17	-
M1R67_RS02250 (M1R67_02250)	463279..464769	+	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
M1R67_RS02255 (M1R67_02255)	464818..465990	-	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
M1R67_RS02260 (M1R67_02260)	466178..466435	+	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
M1R67_RS02265 (M1R67_02265)	466442..466831	+	390	WP_000607077.1	membrane protein	Toxin
M1R67_RS02270 (M1R67_02270)	467601..468686	+	1086	WP_000049106.1	hypothetical protein	-
M1R67_RS02275 (M1R67_02275)	468764..469330	+	567	WP_000651538.1	rhombosortase	-
M1R67_RS02280 (M1R67_02280)	469518..471713	+	2196	WP_001158906.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T243409 WP_000607077.1 NZ_CP096818:466442-466831 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T243409 NZ_OX216966:c6212066-6211716 [Paenibacillus dendritiformis]
TTGATTGTAAAGCGCGGCGACGTTTTTTTTGCGGATTTATCGCCCGTCGTAGGTTCAGAGCAGGGAGGGGTCCGTCCCGT
TCTCGTCATTCAGAATGATATCGGGAACCGGTTCAGCCCAACCGTCATCGTGGCGGCAATTACGGCGCAGATTCAGAAGG
CCAAATTGCCGACCCATGTTGAAATTGACGCGAAGACGCATGGCTTCGACCGCGACTCCGTCATATTGCTGGAACAGATC
CGCACCATCGACAAACAACGGCTCACCGACAAAATAACACACTTAGATGAAGAGACGATGCACAAGGTCGATGACGGGCT
GCTTATCAGCCTCGGATTGATTGATTTTTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT243409 WP_001288210.1 NZ_CP096818:466178-466435 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT243409 NZ_OX216966:c6212351-6212070 [Paenibacillus dendritiformis]
GTGGCTAATATTCAGAACACCAAACGAATTATGATCAGCTTGCCCGACCAACTATTGCAAGAAGTGGACGGTATCGTTGC
TATGGAAAAATCGAATCGAAGCGAGTTCATTCGCCAAGCGATGAAGTTGTATTTGCAAGAGCGCAAGAAGCGTCACATCC
GTGAATCGATGCAGCGCGGCTATATGGAAATGGCCAAAATTAACTTGACGATGGCATCCGAGGCTTTTTACGCAGAAGTC
GAAGCGGATGGCACGCTCGACCGCCTGGTTAGCGGGGTGTAG

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7