Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3144140..3144285 Replicon chromosome
Accession NZ_CP096814
Organism Klebsiella pneumoniae strain Mu1413

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3144147..3144249 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3144140..3144285 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M1R63_RS15445 3139671..3141104 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
M1R63_RS15450 3141220..3141459 + 240 WP_002911393.1 YebV family protein -
M1R63_RS15455 3141557..3141748 + 192 WP_002911395.1 YebW family protein -
M1R63_RS15460 3141745..3142398 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
M1R63_RS15465 3142555..3143523 + 969 WP_004151446.1 VirK/YbjX family protein -
M1R63_RS15470 3143628..3143771 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3144140..3144285 + 146 - - Antitoxin
- 3144147..3144249 - 103 - - Toxin
M1R63_RS15475 3144408..3144746 - 339 WP_002911404.1 YebY family protein -
M1R63_RS15480 3144763..3145632 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
M1R63_RS15485 3145636..3146010 - 375 WP_004151448.1 CopC domain-containing protein YobA -
M1R63_RS15490 3146123..3146353 + 231 WP_002911406.1 DNA polymerase III subunit theta -
M1R63_RS15495 3146432..3147091 + 660 WP_020324964.1 exodeoxyribonuclease X -
M1R63_RS15500 3147095..3149155 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T243393 NZ_CP096814:c3144249-3144147 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT243393 NZ_CP096814:3144140-3144285 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References