Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 1845278..1845788 Replicon chromosome
Accession NZ_CP096812
Organism Acinetobacter baumannii strain 51248

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag M2A29_RS08765 Protein ID WP_039250978.1
Coordinates 1845278..1845541 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M2A29_RS08770 Protein ID WP_272233190.1
Coordinates 1845525..1845788 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2A29_RS08735 (M2A29_08720) 1840527..1841498 + 972 WP_272327754.1 5'/3'-nucleotidase SurE -
M2A29_RS08740 (M2A29_08725) 1841510..1842154 + 645 WP_284626757.1 hypothetical protein -
M2A29_RS08745 (M2A29_08730) 1842189..1842629 - 441 WP_272337000.1 HD domain-containing protein -
M2A29_RS08750 (M2A29_08735) 1842925..1844256 + 1332 WP_284626761.1 HipA domain-containing protein -
M2A29_RS08755 (M2A29_08740) 1844253..1844561 + 309 WP_254946694.1 helix-turn-helix domain-containing protein -
M2A29_RS08760 (M2A29_08745) 1844781..1845212 + 432 WP_227063709.1 hypothetical protein -
M2A29_RS08765 (M2A29_08750) 1845278..1845541 - 264 WP_039250978.1 Txe/YoeB family addiction module toxin Toxin
M2A29_RS08770 (M2A29_08755) 1845525..1845788 - 264 WP_272233190.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M2A29_RS08775 (M2A29_08760) 1846074..1846733 - 660 WP_284626769.1 hypothetical protein -
M2A29_RS08780 (M2A29_08765) 1846860..1847690 - 831 WP_272233188.1 hypothetical protein -
M2A29_RS08785 (M2A29_08770) 1847797..1848192 - 396 WP_272233187.1 hypothetical protein -
M2A29_RS08790 (M2A29_08775) 1849170..1849718 + 549 WP_272233186.1 TetR/AcrR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10321.88 Da        Isoelectric Point: 9.0695

>T243383 WP_039250978.1 NZ_CP096812:c1845541-1845278 [Acinetobacter baumannii]
MTRKISFTPSAWETYMFWQSQDRKTLKRINLLIKDCLRSPFEGLGKPEALIGDLSGFWSRRIDEKNRLVYEVTDSAITIL
SCRYHYE

Download         Length: 264 bp

>T243383 NZ_OX030728:c384890-384783 [Escherichia coli]
ATGACGCTCACGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9764.05 Da        Isoelectric Point: 4.8053

>AT243383 WP_272233190.1 NZ_CP096812:c1845788-1845525 [Acinetobacter baumannii]
MNVLTYTDARKNLKSILDQVVDDADITIITRREGGNAVVMGQDYYNRLMETLHLMSSPSNAAHLAKSIAELRASKAIERE
LLDDEKD

Download         Length: 264 bp

>AT243383 NZ_OX030728:384938-385004 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References