Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1825368..1825462 Replicon chromosome
Accession NZ_CP096666
Organism Yersinia pestis EV76-CN

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1825368..1825461 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1825368..1825462 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0M60_RS07995 (M0M60_07980) 1820940..1821890 + 951 WP_002211090.1 prolyl aminopeptidase -
M0M60_RS08000 (M0M60_07985) 1821950..1822180 - 231 WP_002211091.1 DNA polymerase III subunit theta -
M0M60_RS08005 (M0M60_07990) 1822581..1823090 + 510 WP_002211092.1 non-heme ferritin -
M0M60_RS08010 (M0M60_07995) 1823487..1823873 + 387 WP_002211093.1 CopC domain-containing protein YobA -
M0M60_RS08015 (M0M60_08000) 1823876..1824760 + 885 WP_002211094.1 copper homeostasis membrane protein CopD -
M0M60_RS08020 (M0M60_08005) 1824857..1825198 + 342 WP_002211095.1 YebY family protein -
- 1825368..1825461 + 94 - - Toxin
- 1825368..1825462 - 95 - - Antitoxin
M0M60_RS08025 (M0M60_08010) 1825721..1826047 - 327 WP_002211097.1 DUF1493 family protein -
M0M60_RS08030 (M0M60_08015) 1826041..1826499 - 459 WP_002211098.1 hypothetical protein -
M0M60_RS08035 (M0M60_08020) 1827031..1828191 + 1161 WP_002211099.1 flagellar biosynthesis protein FlhB -
M0M60_RS08040 (M0M60_08025) 1828191..1830269 + 2079 WP_002211100.1 flagellar biosynthesis protein FlhA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 94 bp

>T243242 NZ_CP096666:1825368-1825461 [Yersinia pestis EV76-CN]
TAAGCCTACATTAATACCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATCAGGAATCGTA
TTCGGTCTTTTTTT

Antitoxin


Download         Length: 95 bp

>AT243242 NZ_CP096666:c1825462-1825368 [Yersinia pestis EV76-CN]
TAAAAAAAGACCGAATACGATTCCTGATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGT
ATTAATGTAGGCTTA

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References