Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) virT-relB/YafQ-DinJ
Location 74925..75469 Replicon chromosome
Accession NZ_CP096649
Organism Fenollaria massiliensis strain C0061C2

Toxin (Protein)


Gene name virT Uniprot ID A0A9E7DJF5
Locus tag M1R53_RS00295 Protein ID WP_019214516.1
Coordinates 75194..75469 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M1R53_RS00290 Protein ID WP_249242655.1
Coordinates 74925..75197 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M1R53_RS00275 (M1R53_00275) 70138..71508 - 1371 WP_249242652.1 cation:dicarboxylase symporter family transporter -
M1R53_RS00280 (M1R53_00280) 71789..72778 + 990 WP_249242653.1 PTS sugar transporter subunit IIC -
M1R53_RS00285 (M1R53_00285) 73118..74596 + 1479 WP_249242654.1 C69 family dipeptidase -
M1R53_RS00290 (M1R53_00290) 74925..75197 + 273 WP_249242655.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
M1R53_RS00295 (M1R53_00295) 75194..75469 + 276 WP_019214516.1 type II toxin-antitoxin system YafQ family toxin Toxin
M1R53_RS00300 (M1R53_00300) 75588..76622 - 1035 WP_249242656.1 peptide-methionine (R)-S-oxide reductase MsrB -
M1R53_RS00305 (M1R53_00305) 76633..77625 - 993 WP_249242657.1 LLM class flavin-dependent oxidoreductase -
M1R53_RS00310 (M1R53_00310) 77797..78432 + 636 WP_249242659.1 YARHG domain-containing protein -
M1R53_RS00315 (M1R53_00315) 78984..79181 + 198 WP_249242660.1 DUF4177 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-67)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10529.51 Da        Isoelectric Point: 10.0313

>T243226 WP_019214516.1 NZ_CP096649:75194-75469 [Fenollaria massiliensis]
MKYKVLLTSKFKKDFKLLKKQGKNTDKILAIINKLAKGEFLDAKYKDHPLLGDYLGARECHIEPDLLLIYEKQENILILN
ILRAGSHSNLF

Download         Length: 276 bp

>T243226 NZ_OW970445:58193-58498 [Klebsiella pneumoniae]
ATGCAGTTTAAGGTTTATGCCTATAAAAGAGAGAGCCGCTATCGTCTGTTCGTGGATGTGCAGAGTGACATCATCGATAC
CCCCGGGCGACGGATGGTGATCCCGCTGGCCAGCGCCCGGCTGCTGTCGGATAAGGTTTCCCGTGAACTCTATCCGGTGG
TGCACATCGGGGACGACAGCTACCGCCTGATGACCACGGACATGGCCAGCGTCACGGCCTCCGTCACCGGGGAGGAAGTG
GCCGATCTCAGCCACCGGGAAAATGACATCAAAAATGCGATAAACCTGATGTTCTGGGGAATTTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10215.72 Da        Isoelectric Point: 4.6702

>AT243226 WP_249242655.1 NZ_CP096649:74925-75197 [Fenollaria massiliensis]
MSNTNLNVRIDKDIKKAAEEVYAELGFNMSTAINMFLRASIRKGGIPFDLKLDVPNKETLEAIEEGRRLAMDPSTPLYDN
MEDLRRALEV

Download         Length: 273 bp

>AT243226 NZ_OW970445:57973-58191 [Klebsiella pneumoniae]
ATGAAGCAGCGCATCACTGTCACCATAGACAGCGACAGTTATCAGTTACTGAAATCCGCAGACGTCAATATCTCCGCCCT
GGTGAACAGGGCCATGCAGAATGAGGCCCGTCGTCTGCGTGCCGAACGCTGGCAGGCTGAAAATCAGGAAGGGATGGCCG
AGGTTGCCCGCTTTATTGAGATGAACGGTTCATTCGCCGACGAAAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References