Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2029247..2029518 Replicon chromosome
Accession NZ_CP096587
Organism Escherichia coli strain EC6622

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2029377..2029480 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2029247..2029518 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M1B75_RS09965 2025802..2026464 - 663 WP_000944256.1 exodeoxyribonuclease X -
M1B75_RS09970 2026488..2027144 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
M1B75_RS09975 2027246..2027476 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M1B75_RS09980 2027615..2027989 + 375 WP_000204699.1 CopC domain-containing protein YobA -
M1B75_RS09985 2027993..2028865 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
M1B75_RS09990 2028878..2029219 + 342 WP_000976472.1 YebY family protein -
- 2029247..2029518 - 272 - - Antitoxin
- 2029377..2029480 + 104 - - Toxin
M1B75_RS09995 2029615..2030271 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
M1B75_RS10000 2030272..2030463 - 192 WP_001296140.1 YebW family protein -
M1B75_RS10005 2030568..2030804 - 237 WP_001295499.1 YebV family protein -
M1B75_RS10010 2030922..2032361 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T243188 NZ_CP096587:2029377-2029480 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT243188 NZ_CP096587:c2029518-2029247 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References