Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 3648244..3648803 Replicon chromosome
Accession NZ_CP096583
Organism Rhodococcus pyridinivorans strain PE41

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M1C57_RS16775 Protein ID WP_282706450.1
Coordinates 3648558..3648803 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M1C57_RS16770 Protein ID WP_024102980.1
Coordinates 3648244..3648528 (+) Length 95 a.a.

Genomic Context


M1C57_RS16745M1C57_RS16750M1C57_RS16755M1C57_RS16760M1C57_RS16765M1C57_RS16770M1C57_RS16775M1C57_RS16795M1C57_RS16800M1C57_RS16780M1C57_RS16785M1C57_RS16790M1C57_RS16805
Location: 3643447..3644073 (627 bp)
Type: Others
Protein ID: WP_231911981.1
Location: 3644070..3644498 (429 bp)
Type: Others
Protein ID: WP_024102975.1
Location: 3644503..3646104 (1602 bp)
Type: Others
Protein ID: WP_024102976.1
Location: 3646181..3647209 (1029 bp)
Type: Others
Protein ID: WP_064255975.1
Location: 3647206..3648024 (819 bp)
Type: Others
Protein ID: WP_006551857.1
Location: 3648244..3648528 (285 bp)
Type: Antitoxin
Protein ID: WP_024102980.1
Location: 3648558..3648803 (246 bp)
Type: Toxin
Protein ID: WP_282706450.1
Location: 3650909..3651739 (831 bp)
Type: Others
Protein ID: WP_248689539.1
Location: 3651784..3652755 (972 bp)
Type: Others
Protein ID: WP_006551850.1
Location: 3648860..3649171 (312 bp)
Type: Others
Protein ID: WP_138841658.1
Location: 3649230..3649976 (747 bp)
Type: Others
Protein ID: WP_248689538.1
Location: 3650126..3650788 (663 bp)
Type: Others
Protein ID: WP_094979476.1
Location: 3652792..3653511 (720 bp)
Type: Others
Protein ID: WP_041803971.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
M1C57_RS16745 (M1C57_16745)3643447..3644073+627WP_231911981.1TetR/AcrR family transcriptional regulator-
M1C57_RS16750 (M1C57_16750)3644070..3644498+429WP_024102975.1HIT family protein-
M1C57_RS16755 (M1C57_16755)3644503..3646104+1602WP_024102976.1L-lactate permease-
M1C57_RS16760 (M1C57_16760)3646181..3647209+1029WP_064255975.1Dyp-type peroxidase-
M1C57_RS16765 (M1C57_16765)3647206..3648024+819WP_006551857.1family 1 encapsulin nanocompartment shell protein-
M1C57_RS16770 (M1C57_16770)3648244..3648528+285WP_024102980.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
M1C57_RS16775 (M1C57_16775)3648558..3648803+246WP_282706450.1type II toxin-antitoxin system RelE/ParE family toxinToxin
M1C57_RS16780 (M1C57_16780)3648860..3649171-312WP_138841658.1hypothetical protein-
M1C57_RS16785 (M1C57_16785)3649230..3649976-747WP_248689538.1cutinase family protein-
M1C57_RS16790 (M1C57_16790)3650126..3650788-663WP_094979476.1alpha-ketoglutarate-dependent dioxygenase AlkB-
M1C57_RS16795 (M1C57_16795)3650909..3651739+831WP_248689539.1SDR family oxidoreductase-
M1C57_RS16800 (M1C57_16800)3651784..3652755+972WP_006551850.1phosphotriesterase-
M1C57_RS16805 (M1C57_16805)3652792..3653511-720WP_041803971.12OG-Fe(II) oxygenase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 82 a.a.        Molecular weight: 8999.38 Da        Isoelectric Point: 10.3368

>T243179 WP_282706450.1 NZ_CP096583:3648558-3648803 [Rhodococcus pyridinivorans]
MARSAVRAMARSLPEKVATAVYEFVTGPLLENPKRVGKPLNPPLAPAYSARRGEYRVLYLIDDANRTVEVTAISHRADAY
R

Download         Length: 246 bp

>T243179 NZ_OW970413:835138-835548 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10494.56 Da        Isoelectric Point: 4.2336

>AT243179 WP_024102980.1 NZ_CP096583:3648244-3648528 [Rhodococcus pyridinivorans]
MTTLPVADARAQLSRLVDEAERTHERFEITRNGHRAAVLLGADDYDAMQETIAVLSDTDLLRAHVEGRTEVESGDVVDVQ
ELTQLMRDARSSEE

Download         Length: 285 bp

>AT243179 NZ_OW970413:834891-835157 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References