Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF-MazE
Location 3772731..3773296 Replicon chromosome
Accession NZ_CP096574
Organism Geomonas paludis strain RG22

Toxin (Protein)


Gene name mazE Uniprot ID -
Locus tag M1B72_RS16040 Protein ID WP_183347835.1
Coordinates 3772731..3773054 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name mazF Uniprot ID -
Locus tag M1B72_RS16045 Protein ID WP_183347833.1
Coordinates 3773048..3773296 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M1B72_RS16015 (M1B72_16015) 3768239..3768946 + 708 WP_248646539.1 hypothetical protein -
M1B72_RS16020 (M1B72_16020) 3769128..3769601 + 474 WP_183347845.1 nucleoside 2-deoxyribosyltransferase -
M1B72_RS16025 (M1B72_16025) 3769841..3771067 + 1227 WP_183347843.1 MFS transporter -
M1B72_RS16030 (M1B72_16030) 3771093..3771698 + 606 WP_183347841.1 transglutaminase family protein -
M1B72_RS16035 (M1B72_16035) 3771713..3772618 + 906 WP_183347837.1 MBL fold metallo-hydrolase -
M1B72_RS16040 (M1B72_16040) 3772731..3773054 - 324 WP_183347835.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
M1B72_RS16045 (M1B72_16045) 3773048..3773296 - 249 WP_183347833.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
M1B72_RS16050 (M1B72_16050) 3773383..3777831 - 4449 WP_183347831.1 translocation/assembly module TamB domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-104)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12054.10 Da        Isoelectric Point: 9.9000

>T243172 WP_183347835.1 NZ_CP096574:c3773054-3772731 [Geomonas paludis]
MVAKRFEVYLVNLDPTVGREIRKSRPCLIISPDEMNKYLGTVIVAPMTTKGRDYPTRVSCSFRGKDGQVVLDQIRTIDKS
RLVEKQGRLAKDAQDQVLAILADMFAP

Download         Length: 324 bp

>T243172 NZ_OW970374:c5027580-5026663 [Klebsiella pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCCATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGCGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAATCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9544.71 Da        Isoelectric Point: 4.3331

>AT243172 WP_183347833.1 NZ_CP096574:c3773296-3773048 [Geomonas paludis]
MRTNIIRIGNSQGIRIPKVLLEQSRVGTEVDVEVEDGMIVIRSASRPRDGWTEKFRLMAEQGDDKLVDEGVQTEWDKDEW
EW

Download         Length: 249 bp

>AT243172 NZ_OW970374:c5028344-5027586 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGGCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGAGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References