Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2205434..2205936 Replicon chromosome
Accession NZ_CP096574
Organism Geomonas paludis strain RG22

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M1B72_RS09460 Protein ID WP_183346416.1
Coordinates 2205434..2205688 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag M1B72_RS09465 Protein ID WP_183346415.1
Coordinates 2205685..2205936 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M1B72_RS09445 (M1B72_09445) 2202324..2202800 + 477 WP_129125827.1 transcription elongation factor GreA -
M1B72_RS09450 (M1B72_09450) 2202867..2203064 + 198 WP_183346418.1 DUF1858 domain-containing protein -
M1B72_RS09455 (M1B72_09455) 2203113..2205425 + 2313 WP_248647274.1 ATP-dependent DNA helicase RecG -
M1B72_RS09460 (M1B72_09460) 2205434..2205688 - 255 WP_183346416.1 Txe/YoeB family addiction module toxin Toxin
M1B72_RS09465 (M1B72_09465) 2205685..2205936 - 252 WP_183346415.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M1B72_RS09470 (M1B72_09470) 2206038..2206805 + 768 WP_246404683.1 ATP-binding cassette domain-containing protein -
M1B72_RS09475 (M1B72_09475) 2206805..2207590 + 786 WP_183346414.1 iron export ABC transporter permease subunit FetB -
M1B72_RS09480 (M1B72_09480) 2207845..2208897 - 1053 WP_248647275.1 low specificity L-threonine aldolase -
M1B72_RS09485 (M1B72_09485) 2209004..2209555 - 552 WP_248647331.1 DMT family transporter -
M1B72_RS09490 (M1B72_09490) 2209559..2209831 - 273 Protein_1865 EamA family transporter -
M1B72_RS09495 (M1B72_09495) 2210097..2210840 + 744 WP_183346411.1 basic amino acid ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10138.66 Da        Isoelectric Point: 9.7166

>T243170 WP_183346416.1 NZ_CP096574:c2205688-2205434 [Geomonas paludis]
VKLIFSEFAWEDYLHWQSADKKILKRINTLIREIQRTPYQGIGKPEPLKHALSGFWSRRINDEHRIVYKVDDDAVLIAQL
RYHY

Download         Length: 255 bp

>T243170 NZ_OW970374:4137554-4137772 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACCTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9372.74 Da        Isoelectric Point: 4.8723

>AT243170 WP_183346415.1 NZ_CP096574:c2205936-2205685 [Geomonas paludis]
MNTITYSSARSNLAETMEKVCDDHAPVIITRKAAKPVVMMSLDDYEALEETAYLLRSPKNVRRLMESVAELEAGKGRERE
LVE

Download         Length: 252 bp

>AT243170 NZ_OW970374:4137153-4137527 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References