Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 917363..917748 Replicon chromosome
Accession NZ_CP096570
Organism Xanthomonas translucens pv. undulosa strain Xtu-UPB513

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag MZO50_RS04350 Protein ID WP_003469322.1
Coordinates 917363..917497 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag MZO50_RS04355 Protein ID WP_003469323.1
Coordinates 917596..917748 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MZO50_RS04335 (MZO50_04330) 913802..914725 - 924 WP_003469319.1 MBL fold metallo-hydrolase -
MZO50_RS04340 (MZO50_04335) 914788..916188 - 1401 WP_003469320.1 tryptophan--tRNA ligase -
MZO50_RS04345 (MZO50_04340) 916299..917153 + 855 WP_248646041.1 hypothetical protein -
MZO50_RS04350 (MZO50_04345) 917363..917497 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
MZO50_RS04355 (MZO50_04350) 917596..917748 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
MZO50_RS04360 (MZO50_04355) 917893..918815 - 923 Protein_755 arginase -
MZO50_RS04370 (MZO50_04365) 919221..920039 - 819 WP_047325438.1 SPOR domain-containing protein -
MZO50_RS04375 (MZO50_04370) 920049..920789 - 741 WP_047325439.1 type III pantothenate kinase -
MZO50_RS04380 (MZO50_04375) 920786..921805 - 1020 WP_162489024.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
MZO50_RS04385 (MZO50_04380) 921919..922173 + 255 WP_248646042.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T243166 WP_003469322.1 NZ_CP096570:c917497-917363 [Xanthomonas translucens pv. undulosa]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T243166 NZ_OW970374:796528-796938 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT243166 WP_003469323.1 NZ_CP096570:c917748-917596 [Xanthomonas translucens pv. undulosa]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT243166 NZ_OW970374:796281-796547 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References