Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 101550..102025 Replicon chromosome
Accession NZ_CP096280
Organism Trueperella pyogenes strain EMSSI48

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M1F28_RS00435 Protein ID WP_259146390.1
Coordinates 101750..102025 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M1F28_RS00430 Protein ID WP_259145583.1
Coordinates 101550..101756 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M1F28_RS00420 (M1F28_00420) 96703..97980 + 1278 WP_259145579.1 hypothetical protein -
M1F28_RS00425 (M1F28_00425) 98362..101403 - 3042 WP_259145581.1 type I restriction endonuclease subunit R -
M1F28_RS00430 (M1F28_00430) 101550..101756 + 207 WP_259145583.1 DUF1778 domain-containing protein Antitoxin
M1F28_RS00435 (M1F28_00435) 101750..102025 + 276 WP_259146390.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M1F28_RS00440 (M1F28_00440) 102041..103309 - 1269 WP_259145585.1 restriction endonuclease subunit S -
M1F28_RS00445 (M1F28_00445) 103306..104919 - 1614 WP_259145586.1 type I restriction-modification system subunit M -
M1F28_RS00450 (M1F28_00450) 105116..106261 + 1146 WP_024964407.1 galactokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-88)

Antitoxin

Protein of unknown function DUF6290

(1-66)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10611.22 Da        Isoelectric Point: 10.3790

>T243068 WP_259146390.1 NZ_CP096280:101750-102025 [Trueperella pyogenes]
IVTSFRVEYTKDALKQLKKMDRFDAQLILSWIEKNLSGTDNPRRHGKGLTANRTGEWRYRVGSYRILAQIYDDVLLIEIF
AIGHRRAVYGP

Download         Length: 276 bp

>T243068 NZ_OW969659:2146875-2146978 [Klebsiella oxytoca]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTTTTTTT

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7911.83 Da        Isoelectric Point: 4.2290

>AT243068 WP_259145583.1 NZ_CP096280:101550-101756 [Trueperella pyogenes]
MTLRVSDEDAELVRRYAAFEGKSLSDFMRDAIFEKLEDAEDLATLREVMRNDDGTRYTHEEVLKELGL

Download         Length: 207 bp

>AT243068 NZ_OW969659:c2146985-2146840 [Klebsiella oxytoca]
AAAAGATAAAAAAAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References