Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE(toxin) |
| Location | 101550..102025 | Replicon | chromosome |
| Accession | NZ_CP096280 | ||
| Organism | Trueperella pyogenes strain EMSSI48 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | M1F28_RS00435 | Protein ID | WP_259146390.1 |
| Coordinates | 101750..102025 (+) | Length | 92 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | M1F28_RS00430 | Protein ID | WP_259145583.1 |
| Coordinates | 101550..101756 (+) | Length | 69 a.a. |
Genomic Context
Location: 96703..97980 (1278 bp)
Type: Others
Protein ID: WP_259145579.1
Type: Others
Protein ID: WP_259145579.1
Location: 101550..101756 (207 bp)
Type: Antitoxin
Protein ID: WP_259145583.1
Type: Antitoxin
Protein ID: WP_259145583.1
Location: 101750..102025 (276 bp)
Type: Toxin
Protein ID: WP_259146390.1
Type: Toxin
Protein ID: WP_259146390.1
Location: 105116..106261 (1146 bp)
Type: Others
Protein ID: WP_024964407.1
Type: Others
Protein ID: WP_024964407.1
Location: 98362..101403 (3042 bp)
Type: Others
Protein ID: WP_259145581.1
Type: Others
Protein ID: WP_259145581.1
Location: 102041..103309 (1269 bp)
Type: Others
Protein ID: WP_259145585.1
Type: Others
Protein ID: WP_259145585.1
Location: 103306..104919 (1614 bp)
Type: Others
Protein ID: WP_259145586.1
Type: Others
Protein ID: WP_259145586.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M1F28_RS00420 (M1F28_00420) | 96703..97980 | + | 1278 | WP_259145579.1 | hypothetical protein | - |
| M1F28_RS00425 (M1F28_00425) | 98362..101403 | - | 3042 | WP_259145581.1 | type I restriction endonuclease subunit R | - |
| M1F28_RS00430 (M1F28_00430) | 101550..101756 | + | 207 | WP_259145583.1 | DUF1778 domain-containing protein | Antitoxin |
| M1F28_RS00435 (M1F28_00435) | 101750..102025 | + | 276 | WP_259146390.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| M1F28_RS00440 (M1F28_00440) | 102041..103309 | - | 1269 | WP_259145585.1 | restriction endonuclease subunit S | - |
| M1F28_RS00445 (M1F28_00445) | 103306..104919 | - | 1614 | WP_259145586.1 | type I restriction-modification system subunit M | - |
| M1F28_RS00450 (M1F28_00450) | 105116..106261 | + | 1146 | WP_024964407.1 | galactokinase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10611.22 Da Isoelectric Point: 10.3790
>T243068 WP_259146390.1 NZ_CP096280:101750-102025 [Trueperella pyogenes]
IVTSFRVEYTKDALKQLKKMDRFDAQLILSWIEKNLSGTDNPRRHGKGLTANRTGEWRYRVGSYRILAQIYDDVLLIEIF
AIGHRRAVYGP
IVTSFRVEYTKDALKQLKKMDRFDAQLILSWIEKNLSGTDNPRRHGKGLTANRTGEWRYRVGSYRILAQIYDDVLLIEIF
AIGHRRAVYGP
Download Length: 276 bp
>T243068 NZ_OW969659:2146875-2146978 [Klebsiella oxytoca]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTTTTTTT
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTTTTTTT
Antitoxin
Download Length: 69 a.a. Molecular weight: 7911.83 Da Isoelectric Point: 4.2290
>AT243068 WP_259145583.1 NZ_CP096280:101550-101756 [Trueperella pyogenes]
MTLRVSDEDAELVRRYAAFEGKSLSDFMRDAIFEKLEDAEDLATLREVMRNDDGTRYTHEEVLKELGL
MTLRVSDEDAELVRRYAAFEGKSLSDFMRDAIFEKLEDAEDLATLREVMRNDDGTRYTHEEVLKELGL
Download Length: 207 bp
>AT243068 NZ_OW969659:c2146985-2146840 [Klebsiella oxytoca]
AAAAGATAAAAAAAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGT
AAAAGATAAAAAAAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGT