Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 7664..8448 Replicon plasmid pZA1001
Accession NC_013356
Organism Zymomonas mobilis subsp. mobilis NCIMB 11163

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag ZA10_RS09480 Protein ID WP_012817669.1
Coordinates 7957..8448 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID A0A806DAA8
Locus tag ZA10_RS09475 Protein ID WP_012817668.1
Coordinates 7664..7960 (+) Length 99 a.a.

Genomic Context

ZA10_RS09445ZA10_RS09450ZA10_RS09455ZA10_RS09460ZA10_RS09475ZA10_RS09480ZA10_RS10145ZA10_RS09495ZA10_RS09440ZA10_RS09465ZA10_RS09470ZA10_RS10050
Location: 4195..4425 (231 bp)
Type: Others
Protein ID: WP_012817662.1
Location: 4422..4802 (381 bp)
Type: Others
Protein ID: WP_012817663.1
Location: 5578..5814 (237 bp)
Type: Others
Protein ID: WP_012817664.1
Location: 5811..6392 (582 bp)
Type: Others
Protein ID: WP_012817665.1
Location: 7664..7960 (297 bp)
Type: Antitoxin
Protein ID: WP_012817668.1
Location: 7957..8448 (492 bp)
Type: Toxin
Protein ID: WP_012817669.1
Location: 8636..9405 (770 bp)
Type: Others
Protein ID: Protein_14
Location: 9553..9774 (222 bp)
Type: Others
Protein ID: WP_148207755.1
Location: 3481..3744 (264 bp)
Type: Others
Protein ID: WP_012817661.1
Location: 6526..6786 (261 bp)
Type: Others
Protein ID: WP_012817666.1
Location: 6816..7466 (651 bp)
Type: Others
Protein ID: WP_012817667.1
Location: 11593..11594 (2 bp)
Type: Others
Protein ID: WP_148207756.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
ZA10_RS094403481..3744-264WP_012817661.1type II toxin-antitoxin system RelB/DinJ family antitoxin-
ZA10_RS094454195..4425+231WP_012817662.1hypothetical protein-
ZA10_RS094504422..4802+381WP_012817663.1type II toxin-antitoxin system death-on-curing family toxin-
ZA10_RS094555578..5814+237WP_012817664.1hypothetical protein-
ZA10_RS094605811..6392+582WP_012817665.1zeta toxin family protein-
ZA10_RS094656526..6786-261WP_012817666.1ribbon-helix-helix protein, CopG family-
ZA10_RS094706816..7466-651WP_012817667.1AAA family ATPase-
ZA10_RS094757664..7960+297WP_012817668.1DUF1778 domain-containing proteinAntitoxin
ZA10_RS094807957..8448+492WP_012817669.1GNAT family N-acetyltransferaseToxin
ZA10_RS101458636..9405+770Protein_14IS5 family transposase-
ZA10_RS094959553..9774+222WP_148207755.1transcriptional regulator-
ZA10_RS1005011593..11594-2WP_148207756.1IS5 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..5338053380


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-144)

Antitoxin

Vibrio phage ICP1, Orf50

(8-97)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18011.05 Da        Isoelectric Point: 9.9205

>T24304 WP_012817669.1 NC_013356:7957-8448 [Zymomonas mobilis subsp. mobilis NCIMB 11163]
VTITAPELLSPEHQVELFQSGVESLDLWLKKRALKNQMTGASRTFVACKNRRVMAYYALASSAITIKSAHGRFRRNMPDP
IPVVVLGRLAIDQSLHNQGVGRAMVRDAALRIIQAADTIGIRGMLVHALSDEAKSFYEHIGFEPSPIDPMMLMVTLTDLK
ANI

Download         Length: 492 bp

>T24304 NC_013356:7957-8448 [Zymomonas mobilis subsp. mobilis NCIMB 11163]
GTGACAATAACAGCTCCAGAATTATTATCCCCAGAACATCAAGTTGAGTTATTTCAATCTGGTGTAGAGAGCCTTGATCT
ATGGCTGAAAAAGCGTGCTTTAAAAAATCAAATGACAGGAGCCTCTCGCACATTTGTAGCCTGTAAAAATCGACGGGTGA
TGGCCTATTATGCTCTGGCATCTAGCGCTATCACTATAAAATCAGCCCATGGACGATTTAGGCGTAATATGCCAGATCCT
ATTCCTGTTGTCGTTTTAGGGCGGCTTGCTATTGATCAATCTTTACATAACCAAGGCGTTGGACGAGCAATGGTAAGGGA
TGCAGCCTTAAGGATAATACAGGCAGCTGATACTATCGGAATTAGAGGTATGCTCGTTCATGCGCTATCTGATGAAGCCA
AATCTTTCTACGAACATATCGGTTTCGAACCGTCTCCAATAGACCCAATGATGTTGATGGTTACATTAACCGATTTAAAG
GCTAATATTTAG

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11269.03 Da        Isoelectric Point: 9.8305

>AT24304 WP_012817668.1 NC_013356:7664-7960 [Zymomonas mobilis subsp. mobilis NCIMB 11163]
MVATTTISSPNKREALNIRIKPEERDLIDRAAKIQRKSRTDFVLEAACRAAEEALFDQLIITVDPKAYTNFLTRLDMPPR
PNDRLQKTMQTVAPWDKL

Download         Length: 297 bp

>AT24304 NC_013356:7664-7960 [Zymomonas mobilis subsp. mobilis NCIMB 11163]
ATGGTAGCCACAACAACAATATCCTCACCAAACAAACGAGAAGCGCTGAATATTAGAATTAAACCGGAAGAACGTGATTT
AATAGATCGAGCGGCAAAAATTCAGAGAAAAAGCCGTACTGATTTTGTATTAGAGGCAGCTTGTAGGGCTGCAGAAGAAG
CACTGTTCGATCAATTAATCATTACTGTAGATCCCAAGGCCTATACTAATTTCTTAACACGCCTTGATATGCCACCACGC
CCAAATGATCGGCTGCAAAAAACCATGCAAACGGTAGCTCCATGGGATAAGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A806DAA8

References