Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TsaAT/- |
Location | 1211986..1212463 | Replicon | chromosome |
Accession | NZ_CP096272 | ||
Organism | Staphylococcus aureus strain FJ0318 |
Toxin (Protein)
Gene name | TsaT | Uniprot ID | T1Y7S2 |
Locus tag | M1E49_RS06130 | Protein ID | WP_000052076.1 |
Coordinates | 1212275..1212463 (+) | Length | 63 a.a. |
Antitoxin (Protein)
Gene name | TsaA | Uniprot ID | T1Y6P8 |
Locus tag | M1E49_RS06125 | Protein ID | WP_001059690.1 |
Coordinates | 1211986..1212246 (+) | Length | 87 a.a. |
Genomic Context
Location: 1208245..1208667 (423 bp)
Type: Others
Protein ID: WP_000974447.1
Type: Others
Protein ID: WP_000974447.1
Location: 1209066..1209560 (495 bp)
Type: Others
Protein ID: WP_000569884.1
Type: Others
Protein ID: WP_000569884.1
Location: 1209714..1210331 (618 bp)
Type: Others
Protein ID: WP_000255561.1
Type: Others
Protein ID: WP_000255561.1
Location: 1211210..1211446 (237 bp)
Type: Others
Protein ID: WP_000368687.1
Type: Others
Protein ID: WP_000368687.1
Location: 1211986..1212246 (261 bp)
Type: Antitoxin
Protein ID: WP_001059690.1
Type: Antitoxin
Protein ID: WP_001059690.1
Location: 1212275..1212463 (189 bp)
Type: Toxin
Protein ID: WP_000052076.1
Type: Toxin
Protein ID: WP_000052076.1
Location: 1212651..1213220 (570 bp)
Type: Others
Protein ID: WP_001106654.1
Type: Others
Protein ID: WP_001106654.1
Location: 1213308..1213592 (285 bp)
Type: Others
Protein ID: WP_001004395.1
Type: Others
Protein ID: WP_001004395.1
Location: 1213654..1213872 (219 bp)
Type: Others
Protein ID: WP_000005889.1
Type: Others
Protein ID: WP_000005889.1
Location: 1207381..1208097 (717 bp)
Type: Others
Protein ID: WP_000150021.1
Type: Others
Protein ID: WP_000150021.1
Location: 1210404..1210985 (582 bp)
Type: Others
Protein ID: WP_001140690.1
Type: Others
Protein ID: WP_001140690.1
Location: 1211443..1211646 (204 bp)
Type: Others
Protein ID: WP_000145163.1
Type: Others
Protein ID: WP_000145163.1
Location: 1214367..1214567 (201 bp)
Type: Others
Protein ID: WP_001059082.1
Type: Others
Protein ID: WP_001059082.1
Location: 1214924..1215610 (687 bp)
Type: Others
Protein ID: WP_001641381.1
Type: Others
Protein ID: WP_001641381.1
Location: 1215951..1216460 (510 bp)
Type: Others
Protein ID: WP_000824480.1
Type: Others
Protein ID: WP_000824480.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M1E49_RS06090 (1207381) | 1207381..1208097 | - | 717 | WP_000150021.1 | type I 3-dehydroquinate dehydratase | - |
M1E49_RS06095 (1208245) | 1208245..1208667 | + | 423 | WP_000974447.1 | organic hydroperoxide resistance protein | - |
M1E49_RS06100 (1209066) | 1209066..1209560 | + | 495 | WP_000569884.1 | GNAT family N-acetyltransferase | - |
M1E49_RS06105 (1209714) | 1209714..1210331 | + | 618 | WP_000255561.1 | LysE/ArgO family amino acid transporter | - |
M1E49_RS06110 (1210404) | 1210404..1210985 | - | 582 | WP_001140690.1 | histidine phosphatase family protein | - |
M1E49_RS06115 (1211210) | 1211210..1211446 | + | 237 | WP_000368687.1 | hypothetical protein | - |
M1E49_RS06120 (1211443) | 1211443..1211646 | - | 204 | WP_000145163.1 | sterile alpha motif-like domain-containing protein | - |
M1E49_RS06125 (1211986) | 1211986..1212246 | + | 261 | WP_001059690.1 | hypothetical protein | Antitoxin |
M1E49_RS06130 (1212275) | 1212275..1212463 | + | 189 | WP_000052076.1 | hypothetical protein | Toxin |
M1E49_RS06135 (1212651) | 1212651..1213220 | + | 570 | WP_001106654.1 | lipoprotein N-acylation protein LnsA | - |
M1E49_RS06140 (1213308) | 1213308..1213592 | + | 285 | WP_001004395.1 | hypothetical protein | - |
M1E49_RS06145 (1213654) | 1213654..1213872 | + | 219 | WP_000005889.1 | hypothetical protein | - |
M1E49_RS06150 (1214367) | 1214367..1214567 | - | 201 | WP_001059082.1 | cold-shock protein | - |
M1E49_RS06155 (1214924) | 1214924..1215610 | - | 687 | WP_001641381.1 | thermonuclease family protein | - |
M1E49_RS06160 (1215951) | 1215951..1216460 | - | 510 | WP_000824480.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 63 a.a. Molecular weight: 7142.82 Da Isoelectric Point: 9.9971
>T243039 WP_000052076.1 NZ_CP096272:1212275-1212463 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL
Download Length: 189 bp
>T243039 NZ_OW968348:59824-60240 [Klebsiella oxytoca]
GTGAACAAGACCTATATGCTCGACACCTGTATCTGCTCGTTCATCATGCGCGAGCAGCCGGAAGCCGTCCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGCCAGCGCATCGTTGTCTCGGCCATCACTTATTCTGAAATGCGCTTCGGGGCCACCGGCC
CGAAGGCCTCCCCGCGCCACGTCGAGCTGGTCGACGCGTTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGACGCCACCACGGAGATTAAGGTGGCGCTGCGAATGGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGGCACGCCATCGCCGCCGGTGCCGTGCTGGTGACGAATAATACGCGGGAATTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA
GTGAACAAGACCTATATGCTCGACACCTGTATCTGCTCGTTCATCATGCGCGAGCAGCCGGAAGCCGTCCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGCCAGCGCATCGTTGTCTCGGCCATCACTTATTCTGAAATGCGCTTCGGGGCCACCGGCC
CGAAGGCCTCCCCGCGCCACGTCGAGCTGGTCGACGCGTTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGACGCCACCACGGAGATTAAGGTGGCGCTGCGAATGGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGGCACGCCATCGCCGCCGGTGCCGTGCTGGTGACGAATAATACGCGGGAATTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9940.09 Da Isoelectric Point: 4.0624
>AT243039 WP_001059690.1 NZ_CP096272:1211986-1212246 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG
Download Length: 261 bp
>AT243039 NZ_OW968348:59597-59827 [Klebsiella oxytoca]
ATGAGAACTGTATCCATTTTTAAAAACGGCAATAACCGCGCCATTCGTCTGCCCCGCGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATTATTTTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGTTCG
AGAAGGCAGACCCGGACTTTATGGCGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGATTTAACCTGTGA
ATGAGAACTGTATCCATTTTTAAAAACGGCAATAACCGCGCCATTCGTCTGCCCCGCGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATTATTTTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGTTCG
AGAAGGCAGACCCGGACTTTATGGCGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGATTTAACCTGTGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0VP18 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0VN56 |