Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1989719..1989864 Replicon chromosome
Accession NZ_CP096260
Organism Klebsiella pneumoniae strain KP19-2796

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1989755..1989857 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1989719..1989864 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0M88_RS09655 1984849..1986909 + 2061 WP_004151449.1 oligopeptidase B -
M0M88_RS09660 1986913..1987572 - 660 WP_020324964.1 exodeoxyribonuclease X -
M0M88_RS09665 1987651..1987881 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M0M88_RS09670 1987994..1988368 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M0M88_RS09675 1988372..1989241 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
M0M88_RS09680 1989258..1989596 + 339 WP_002911404.1 YebY family protein -
- 1989719..1989864 - 146 - - Antitoxin
- 1989755..1989857 + 103 - - Toxin
M0M88_RS09685 1990233..1990376 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M0M88_RS09690 1990481..1991449 - 969 WP_004151446.1 VirK/YbjX family protein -
M0M88_RS09695 1991606..1992259 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M0M88_RS09700 1992256..1992447 - 192 WP_002911395.1 YebW family protein -
M0M88_RS09705 1992545..1992784 - 240 WP_002911393.1 YebV family protein -
M0M88_RS09710 1992900..1994333 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T242998 NZ_CP096260:1989755-1989857 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT242998 NZ_CP096260:c1989864-1989719 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References