Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_XRE
Location 4089132..4089840 Replicon chromosome
Accession NZ_CP096258
Organism Providencia rettgeri strain Pre20-95

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M0M83_RS18700 Protein ID WP_232062930.1
Coordinates 4089451..4089840 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M0M83_RS18695 Protein ID WP_004905885.1
Coordinates 4089132..4089461 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0M83_RS18680 (M0M83_18685) 4085219..4086190 - 972 WP_213913369.1 efflux RND transporter periplasmic adaptor subunit -
M0M83_RS18685 (M0M83_18690) 4086706..4088391 + 1686 WP_125890726.1 sensor histidine kinase -
M0M83_RS18690 (M0M83_18695) 4088411..4089127 + 717 WP_213913370.1 two-component system response regulator BtsR -
M0M83_RS18695 (M0M83_18700) 4089132..4089461 - 330 WP_004905885.1 helix-turn-helix domain-containing protein Antitoxin
M0M83_RS18700 (M0M83_18705) 4089451..4089840 - 390 WP_232062930.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M0M83_RS18705 (M0M83_18710) 4089994..4091850 - 1857 WP_248467171.1 DEAD/DEAH family ATP-dependent RNA helicase -
M0M83_RS18710 (M0M83_18715) 4092021..4092938 - 918 WP_248467172.1 lipoprotein NlpI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(4-124)

Antitoxin

Cro/C1-type helix-turn-helix domain

(53-93)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14528.83 Da        Isoelectric Point: 8.8281

>T242990 WP_232062930.1 NZ_CP096258:c4089840-4089451 [Providencia rettgeri]
VAFYKISSFKRSTKKIKIMDKHLLKAANEVLAGVYEADLGSGVIKKRIAINGKGKSGGVRVIIFFKVSHHLFFADGWEKC
NIAAKGVKEIEDDELDAYKNLSRLFLNYTDDKIADLVLHNILEELTDEQ

Download         Length: 390 bp

>T242990 NZ_OW968278:c97039-96623 [Escherichia coli]
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAACCTGAAGCATTGCTTAAGCACCT
GGAGCAGTCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGTGCCACCGGTC
CGAAGGCCTCGCCACGCCACGTGCAACTGGTTGACGCGTTCTGTGAGAGGCTCGATGCCGTCCTGCCGTGGGACCGCGCC
GCGGTGGATGCGACCACGGAGATTAAGGTGGCACTGCGTCTCGCCGGCACGCCGATCGGTCCGAACGACACGGCGATAGC
CGGACACGCCATCGCTGCCTGTGCCATTCTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12235.50 Da        Isoelectric Point: 10.3803

>AT242990 WP_004905885.1 NZ_CP096258:c4089461-4089132 [Providencia rettgeri]
MSNKLENMLELAKELHQVDAAPKSLVTDLEQKVGNRKINNKIKVVPMMSGAQIKQLRAQYGMSQAMLALALGMSKESVSK
WEREEKKPSGPALRMLHLIEQRGPEILII

Download         Length: 330 bp

>AT242990 NZ_OW968278:c97266-97036 [Escherichia coli]
ATGAGAACCGTATCCATTTTTAAAAATGGCAACAACCGTGCTATCCGCCTTCCACGCGATCTGGATTTTGAGGGGGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGCCCCGTCCGGCCGACCTGGGGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGACTTTATGACGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGAGTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References