Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 4082187..4082778 Replicon chromosome
Accession NZ_CP096258
Organism Providencia rettgeri strain Pre20-95

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M0M83_RS18660 Protein ID WP_125890662.1
Coordinates 4082187..4082504 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M0M83_RS18665 Protein ID WP_125890663.1
Coordinates 4082485..4082778 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0M83_RS18630 (M0M83_18635) 4077891..4078142 - 252 WP_125890656.1 DUF1471 domain-containing protein -
M0M83_RS18635 (M0M83_18640) 4078413..4078751 + 339 WP_248467166.1 GIY-YIG nuclease family protein -
M0M83_RS18640 (M0M83_18645) 4078724..4079227 - 504 WP_248467167.1 N-acetyltransferase -
M0M83_RS18645 (M0M83_18650) 4079221..4079745 - 525 WP_125890659.1 SCP2 domain-containing protein -
M0M83_RS18650 (M0M83_18655) 4080259..4081254 + 996 WP_125890660.1 peptidase U32 family protein -
M0M83_RS18655 (M0M83_18660) 4081272..4082147 + 876 WP_248467168.1 U32 family peptidase -
M0M83_RS18660 (M0M83_18665) 4082187..4082504 - 318 WP_125890662.1 type II toxin-antitoxin system YafQ family toxin Toxin
M0M83_RS18665 (M0M83_18670) 4082485..4082778 - 294 WP_125890663.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
M0M83_RS18670 (M0M83_18675) 4082908..4084062 - 1155 WP_125890664.1 ABC transporter permease -
M0M83_RS18675 (M0M83_18680) 4084062..4085207 - 1146 WP_248467169.1 ABC transporter permease -
M0M83_RS18680 (M0M83_18685) 4085219..4086190 - 972 WP_213913369.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(14-104)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(12-77)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 12254.02 Da        Isoelectric Point: 9.7799

>T242989 WP_125890662.1 NZ_CP096258:c4082504-4082187 [Providencia rettgeri]
MTQKPSNKRAKQPRQVAYTPTFKKSWERYNRAGRRDMNTAVLVMEILFSQKMIPKEYLDHELEGHEWQGARELHIGGDFL
LVYRLSDKGNLITFVDIGSHSELFG

Download         Length: 318 bp

>T242989 NZ_OW968278:c56378-56229 [Escherichia coli]
ATGACGAAATATGCCCTTATCGGGTTGCTCGCCGTGTGCGCCACGGTGTTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAACTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11022.80 Da        Isoelectric Point: 6.9831

>AT242989 WP_125890663.1 NZ_CP096258:c4082778-4082485 [Providencia rettgeri]
MSTLLKMKTTDVRSRIDEQLKAEATSVLQDCGLTISAAIRLFLEQVVQEQRVPFEIKRKQPSLKTTLALKEAKAIEQHYD
SINEMMVELSKVDSEAK

Download         Length: 294 bp

>AT242989 NZ_OW968278:56422-56483 [Escherichia coli]
TTAAGGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References