Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3951154..3951950 Replicon chromosome
Accession NZ_CP096258
Organism Providencia rettgeri strain Pre20-95

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag M0M83_RS18070 Protein ID WP_125890580.1
Coordinates 3951154..3951666 (-) Length 171 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag M0M83_RS18075 Protein ID WP_102138080.1
Coordinates 3951663..3951950 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0M83_RS18055 (M0M83_18060) 3947206..3948177 - 972 WP_102138076.1 DNA-binding transcriptional regulator DsdC -
M0M83_RS18060 (M0M83_18065) 3948394..3949731 + 1338 WP_213913659.1 D-serine transporter DsdX -
M0M83_RS18065 (M0M83_18070) 3949744..3951078 + 1335 WP_213913660.1 D-serine ammonia-lyase -
M0M83_RS18070 (M0M83_18075) 3951154..3951666 - 513 WP_125890580.1 GNAT family N-acetyltransferase Toxin
M0M83_RS18075 (M0M83_18080) 3951663..3951950 - 288 WP_102138080.1 DUF1778 domain-containing protein Antitoxin
M0M83_RS18080 (M0M83_18085) 3952199..3953254 - 1056 WP_213913662.1 osmoprotectant NAGGN system M42 family peptidase -
M0M83_RS18085 (M0M83_18090) 3953259..3954029 - 771 WP_125890582.1 FCD domain-containing protein -
M0M83_RS18090 (M0M83_18095) 3954060..3954863 - 804 WP_213913663.1 ATP-binding cassette domain-containing protein -
M0M83_RS18095 (M0M83_18100) 3954863..3956677 - 1815 WP_213913664.1 dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(34-147)

Antitoxin

Vibrio phage ICP1, Orf50

(14-87)


Sequences

Toxin        


Download         Length: 171 a.a.        Molecular weight: 18325.20 Da        Isoelectric Point: 9.9566

>T242988 WP_125890580.1 NZ_CP096258:c3951666-3951154 [Providencia rettgeri]
MTLKLTAPEPLKTGHLLEGFSSGEEALDLWLKTRAMSNQNSGASRTFVTTSDNQVMGYYALSTGVVSTNQAVGRFRRNMP
SDIPVILLGRLAVDTRAKGLGVGRGLVKDACHRVIQASGLVGIRGVVVHALTDNAKRFYEHIGFVPSPLDSMMLMITLAD
LQFALGIHSN

Download         Length: 513 bp

>T242988 NZ_OW968277:c5139455-5139348 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACAACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGTGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10607.97 Da        Isoelectric Point: 4.8660

>AT242988 WP_102138080.1 NZ_CP096258:c3951950-3951663 [Providencia rettgeri]
MSTQNDVAVTRSSLNLRIKPEDKILIDRAANAVGKNRTEFVLEAARRAAEETLADLRVINVSAEVYQEFISQLDAAPSSN
EALRKTMMSKSPWEE

Download         Length: 288 bp

>AT242988 NZ_OW968277:5139503-5139569 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References