Detailed information of TA system TA242980

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/LOTUS_5_Limkain_b1-Phd
• Location: 7577701..7578404
• Replicon: chromosome
• Accession: NZ_CP096255
• Organism: Bradyrhizobium barranii subsp. apii strain 1S5

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: HAP41_RS36395
• Protein ID: WP_166084831.1
• Coordinates: 7577979..7578404 (+)
• Length: 142 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A8T5VAC8
• Locus tag: HAP41_RS36390
• Protein ID: WP_028148610.1
• Coordinates: 7577701..7577982 (+)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HAP41_RS36370 (HAP41_0000036370)	7572774..7573748	-	975	WP_063985186.1	sugar ABC transporter permease	-
HAP41_RS36375 (HAP41_0000036375)	7573748..7574833	-	1086	WP_166084837.1	ABC transporter ATP-binding protein	-
HAP41_RS36380 (HAP41_0000036380)	7574848..7575924	-	1077	WP_063985188.1	ABC transporter ATP-binding protein	-
HAP41_RS36385 (HAP41_0000036385)	7575921..7577471	-	1551	WP_166084835.1	glycerol-3-phosphate dehydrogenase	-
HAP41_RS36390 (HAP41_0000036390)	7577701..7577982	+	282	WP_028148610.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
HAP41_RS36395 (HAP41_0000036395)	7577979..7578404	+	426	WP_166084831.1	type II toxin-antitoxin system VapC family toxin	Toxin
HAP41_RS36400 (HAP41_0000036400)	7578409..7579257	-	849	WP_063985191.1	DeoR/GlpR family DNA-binding transcription regulator	-
HAP41_RS36405 (HAP41_0000036405)	7579349..7580047	-	699	WP_039146404.1	HAD-IA family hydrolase	-
HAP41_RS36410 (HAP41_0000036410)	7580202..7580651	+	450	WP_166084819.1	nuclear transport factor 2 family protein	-
HAP41_RS36415 (HAP41_0000036415)	7580979..7581374	+	396	WP_155795382.1	nuclear transport factor 2 family protein	-
HAP41_RS36420 (HAP41_0000036420)	7581642..7581833	-	192	WP_028134810.1	hypothetical protein	-
HAP41_RS36425 (HAP41_0000036425)	7582054..7582464	-	411	WP_063985193.1	acyl-CoA thioesterase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-123)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (14-77)

Sequences

Toxin

Protein

• Length: 142 a.a.
• Molecular weight: 15387.62 Da
• Isoelectric Point: 5.1649

>T242980 WP_166084831.1 NZ_CP096255:7577979-7578404 [Bradyrhizobium barranii subsp. apii]
VNLLLDTNVLSEVQRPAPSAKVLAWLDTVDEDRAFISVASIAELRRGIALLDDGRRRAALGAWLAHDLPARFAQRILPID
HAVAERWGDLMAQSRRNGVALSVMDGFFAATALANELTLVTRNVKDFAAFGVPLLDPWSDA

Nucleotide

• Length: 426 bp

>T242980 NZ_CP096255:7577979-7578404 [Bradyrhizobium barranii subsp. apii]
GTGAACCTGCTCCTCGACACCAACGTGCTGTCGGAGGTTCAGCGGCCGGCGCCTTCCGCGAAAGTCCTGGCATGGCTCGA
TACGGTCGATGAGGATCGCGCGTTCATCAGCGTTGCCTCGATCGCCGAGCTTCGTCGCGGCATCGCCCTGCTGGACGATG
GCCGTCGGCGCGCCGCGCTGGGCGCTTGGCTCGCCCATGACCTGCCGGCTCGGTTCGCGCAGCGCATCCTGCCGATCGAC
CACGCGGTCGCTGAGCGCTGGGGCGACCTGATGGCGCAGAGCCGTCGCAATGGCGTTGCGTTGTCCGTGATGGACGGCTT
CTTTGCGGCCACCGCGCTCGCCAACGAGCTCACGCTCGTCACACGCAATGTGAAGGATTTTGCGGCCTTCGGCGTTCCGC
TGCTTGACCCATGGAGCGACGCCTAA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10250.47 Da
• Isoelectric Point: 5.1409

>AT242980 WP_028148610.1 NZ_CP096255:7577701-7577982 [Bradyrhizobium barranii subsp. apii]
MTDRSTAPDSPPTDTWTLANAKARLSEVVDRAQTGPQIITRHGRPNAVVVSADEWARKTARKGTLAEFLLASPLRGADLE
LERVQDEPRDEMP

Nucleotide

• Length: 282 bp

>AT242980 NZ_CP096255:7577701-7577982 [Bradyrhizobium barranii subsp. apii]
ATGACAGACCGCAGCACCGCCCCCGATTCGCCCCCGACTGACACGTGGACGCTCGCCAATGCCAAGGCGCGCCTTTCCGA
GGTGGTCGATCGCGCCCAAACTGGCCCCCAGATCATCACCCGACACGGCAGACCCAATGCGGTTGTCGTTTCCGCGGATG
AATGGGCGCGAAAGACGGCACGCAAAGGCACGCTGGCCGAATTCCTGCTGGCTTCGCCGCTGCGCGGTGCCGACCTCGAA
CTTGAACGGGTGCAGGACGAACCGCGCGACGAGATGCCGTGA