Detailed information of TA system TA242979

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/Tad-HTH_37
• Location: 6589695..6590291
• Replicon: chromosome
• Accession: NZ_CP096251
• Organism: Bradyrhizobium barranii subsp. apii strain 38S5

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: J4G48_RS31580
• Protein ID: WP_225049103.1
• Coordinates: 6590073..6590291 (-)
• Length: 73 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: J4G48_RS31575
• Protein ID: WP_208070348.1
• Coordinates: 6589695..6590018 (-)
• Length: 108 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J4G48_RS31550 (J4G48_0031550)	6585083..6586297	-	1215	WP_208070357.1	virulence-associated E family protein	-
J4G48_RS31555 (J4G48_0031555)	6586895..6588094	+	1200	WP_208070355.1	site-specific integrase	-
J4G48_RS31560 (J4G48_0031560)	6588094..6588471	+	378	WP_208070354.1	hypothetical protein	-
J4G48_RS31565 (J4G48_0031565)	6588600..6588854	-	255	WP_208070352.1	hypothetical protein	-
J4G48_RS31570 (J4G48_0031570)	6588966..6589232	-	267	WP_208070350.1	hypothetical protein	-
J4G48_RS50925	6589368..6589502	+	135	WP_256508371.1	hypothetical protein	-
J4G48_RS31575 (J4G48_0031575)	6589695..6590018	-	324	WP_208070348.1	helix-turn-helix transcriptional regulator	Antitoxin
J4G48_RS31580 (J4G48_0031580)	6590073..6590291	-	219	WP_225049103.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
J4G48_RS31585 (J4G48_0031585)	6591596..6592431	+	836	Protein_6303	IS5 family transposase	-
J4G48_RS31590 (J4G48_0031590)	6593382..6593612	-	231	WP_208070345.1	hypothetical protein	-
J4G48_RS31595 (J4G48_0031595)	6593961..6594176	+	216	WP_208070343.1	hypothetical protein	-
J4G48_RS31600 (J4G48_0031600)	6594239..6594442	-	204	WP_208070341.1	cold-shock protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	6565926..6652942	87016

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (1-65)

Antitoxin

• HigA2-like, helix-turn-helix domain (13-92)

Sequences

Toxin

Protein

• Length: 73 a.a.
• Molecular weight: 7914.31 Da
• Isoelectric Point: 11.2848

>T242979 WP_225049103.1 NZ_CP096251:c6590291-6590073 [Bradyrhizobium barranii subsp. apii]
IGFALRAAQKGGKSENAKPLKGFSGASILQIKCDFDGDTFRAVYTVRLKGTIYVLHAFQKKSRRVAKLLRAT

Nucleotide

• Length: 219 bp

>T242979 NZ_OW968277:c2475919-2475746 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTTCTGGTCGGAATAACCTGGCCAATGAGTTTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin

Protein

• Length: 108 a.a.
• Molecular weight: 11497.29 Da
• Isoelectric Point: 10.4688

>AT242979 WP_208070348.1 NZ_CP096251:c6590018-6589695 [Bradyrhizobium barranii subsp. apii]
MSKARSVKGSGNVFADIGVPDAEEHLAKADLVLGIASIIRAKGLSQSQAARLIGIAQPDVSRLMRGNFDGFSYERLFTLL
NALGENVRIVVSDAKPKTKARLQLEFA

Nucleotide

• Length: 324 bp

>AT242979 NZ_OW968277:c2476243-2475947 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTCAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAGCATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG