Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2072075..2072220 Replicon chromosome
Accession NZ_CP096242
Organism Klebsiella pneumoniae subsp. pneumoniae strain DD01665

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2072111..2072213 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2072075..2072220 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0535_RS09915 2067205..2069265 + 2061 WP_004151449.1 oligopeptidase B -
M0535_RS09920 2069269..2069928 - 660 WP_002911407.1 exodeoxyribonuclease X -
M0535_RS09925 2070007..2070237 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M0535_RS09930 2070350..2070724 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M0535_RS09935 2070728..2071597 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
M0535_RS09940 2071614..2071952 + 339 WP_002911404.1 YebY family protein -
- 2072075..2072220 - 146 - - Antitoxin
- 2072111..2072213 + 103 - - Toxin
M0535_RS09945 2072588..2072731 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M0535_RS09950 2072836..2073804 - 969 WP_014907334.1 VirK/YbjX family protein -
M0535_RS09955 2073961..2074614 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M0535_RS09960 2074611..2074802 - 192 WP_002911395.1 YebW family protein -
M0535_RS09965 2074900..2075139 - 240 WP_002911393.1 YebV family protein -
M0535_RS09970 2075255..2076688 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T242958 NZ_CP096242:2072111-2072213 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT242958 NZ_CP096242:c2072220-2072075 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References