Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2077218..2077363 Replicon chromosome
Accession NZ_CP096234
Organism Klebsiella pneumoniae subsp. pneumoniae strain DD02357

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2077254..2077356 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2077218..2077363 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0537_RS10000 2072348..2074408 + 2061 WP_004151449.1 oligopeptidase B -
M0537_RS10005 2074412..2075071 - 660 WP_002911407.1 exodeoxyribonuclease X -
M0537_RS10010 2075150..2075380 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M0537_RS10015 2075493..2075867 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M0537_RS10020 2075871..2076740 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
M0537_RS10025 2076757..2077095 + 339 WP_002911404.1 YebY family protein -
- 2077218..2077363 - 146 - - Antitoxin
- 2077254..2077356 + 103 - - Toxin
M0537_RS10030 2077731..2077874 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M0537_RS10035 2077979..2078946 - 968 Protein_1960 VirK/YbjX family protein -
M0537_RS10040 2079103..2079756 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M0537_RS10045 2079753..2079944 - 192 WP_002911395.1 YebW family protein -
M0537_RS10050 2080042..2080281 - 240 WP_002911393.1 YebV family protein -
M0537_RS10055 2080397..2081830 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T242918 NZ_CP096234:2077254-2077356 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT242918 NZ_CP096234:c2077363-2077218 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References