Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2009632..2009777 Replicon chromosome
Accession NZ_CP096230
Organism Klebsiella pneumoniae subsp. pneumoniae strain H39

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2009668..2009770 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2009632..2009777 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0538_RS09595 2004762..2006822 + 2061 WP_004151449.1 oligopeptidase B -
M0538_RS09600 2006826..2007485 - 660 WP_002911407.1 exodeoxyribonuclease X -
M0538_RS09605 2007564..2007794 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M0538_RS09610 2007907..2008281 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M0538_RS09615 2008285..2009154 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
M0538_RS09620 2009171..2009509 + 339 WP_002911404.1 YebY family protein -
- 2009632..2009777 - 146 - - Antitoxin
- 2009668..2009770 + 103 - - Toxin
M0538_RS09625 2010145..2010288 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M0538_RS09630 2010393..2011361 - 969 WP_014907334.1 VirK/YbjX family protein -
M0538_RS09635 2011518..2012171 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M0538_RS09640 2012168..2012359 - 192 WP_002911395.1 YebW family protein -
M0538_RS09645 2012457..2012696 - 240 WP_002911393.1 YebV family protein -
M0538_RS09650 2012812..2014245 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T242897 NZ_CP096230:2009668-2009770 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT242897 NZ_CP096230:c2009777-2009632 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References