242889

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4668967..4669328 Replicon chromosome
Accession NZ_CP096227
Organism Xanthomonas citri pv. citri strain CQ13

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XCQ_RS20105 Protein ID WP_005914328.1
Coordinates 4668967..4669101 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XCQ_RS20110 Protein ID WP_003486606.1
Coordinates 4669176..4669328 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCQ_RS20085 (XCQ_20085) 4664105..4665796 - 1692 WP_015471463.1 M28 family metallopeptidase -
XCQ_RS20090 (XCQ_20090) 4665988..4666932 - 945 WP_015463704.1 MBL fold metallo-hydrolase -
XCQ_RS20095 (XCQ_20095) 4667061..4668350 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
XCQ_RS20100 (XCQ_20100) 4668531..4668740 - 210 WP_003486601.1 CsbD family protein -
XCQ_RS20105 (XCQ_20105) 4668967..4669101 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XCQ_RS20110 (XCQ_20110) 4669176..4669328 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XCQ_RS20115 (XCQ_20115) 4669435..4670358 - 924 WP_005927745.1 arginase -
XCQ_RS20120 (XCQ_20120) 4670679..4671131 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
XCQ_RS20125 (XCQ_20125) 4671195..4671554 + 360 WP_003486613.1 hypothetical protein -
XCQ_RS20130 (XCQ_20130) 4671651..4672568 + 918 WP_011052673.1 hypothetical protein -
XCQ_RS20135 (XCQ_20135) 4672565..4673107 + 543 WP_003486615.1 GTPase -
XCQ_RS20140 (XCQ_20140) 4673545..4674228 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T242889 WP_005914328.1 NZ_CP096227:c4669101-4668967 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T242889 NZ_OW967975:c3753620-3753222 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCCTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGAGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGGGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT242889 WP_003486606.1 NZ_CP096227:c4669328-4669176 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT242889 NZ_OW967975:c3753916-3753623 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References