Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 2568961..2569594 Replicon chromosome
Accession NZ_CP096227
Organism Xanthomonas citri pv. citri strain CQ13

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag XCQ_RS11200 Protein ID WP_015463212.1
Coordinates 2568961..2569374 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID M4TWF0
Locus tag XCQ_RS11205 Protein ID WP_015463213.1
Coordinates 2569361..2569594 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCQ_RS11185 (XCQ_11185) 2564899..2566833 + 1935 WP_230598900.1 TonB-dependent siderophore receptor -
XCQ_RS11190 (XCQ_11190) 2567042..2568556 + 1515 WP_015463210.1 conjugal transfer protein TraG N-terminal domain-containing protein -
XCQ_RS11195 (XCQ_11195) 2568572..2568934 - 363 WP_015463211.1 DUF3742 family protein -
XCQ_RS11200 (XCQ_11200) 2568961..2569374 - 414 WP_015463212.1 PIN domain-containing protein Toxin
XCQ_RS11205 (XCQ_11205) 2569361..2569594 - 234 WP_015463213.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
XCQ_RS11210 (XCQ_11210) 2569876..2570883 + 1008 WP_015463214.1 DUF4917 family protein -
XCQ_RS11215 (XCQ_11215) 2571016..2571471 - 456 WP_015463215.1 hypothetical protein -
XCQ_RS11220 (XCQ_11220) 2571866..2572441 + 576 WP_011051400.1 sigma-70 family RNA polymerase sigma factor -
XCQ_RS11225 (XCQ_11225) 2572422..2573471 + 1050 WP_011051401.1 FecR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-119)

Antitoxin

SpoVT-AbrB domain

(5-45)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15221.65 Da        Isoelectric Point: 6.3225

>T242887 WP_015463212.1 NZ_CP096227:c2569374-2568961 [Xanthomonas citri pv. citri]
MAAGKGKVFLDSNVVLYLLSEDAVKADGAEALLQRRPVISVQVLNEVTHVCVRKLKMGWDEVGQFLALVRSFCKIVPLTV
DVHDRARQLAERHQLSFYDACIVAAAAIEGCQTLYSEDMHHGLIIEESLSIRNPFNV

Download         Length: 414 bp

>T242887 NZ_OW967975:2713864-2713971 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8663.97 Da        Isoelectric Point: 8.7848

>AT242887 WP_015463213.1 NZ_CP096227:c2569594-2569361 [Xanthomonas citri pv. citri]
MQVAKWGNSLAVRLPSSLVEALELREGDDIEIVVDDPRLFAVRKKPGPEAMLERLRAFRGKLPADFKFNRDEANGRG

Download         Length: 234 bp

>AT242887 NZ_OW967975:c2713817-2713751 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4TWF0

References